Nels and Vincent discuss an analysis of the drivers of evolution of SARS-CoV-2 during chronic infections, indicating that a tradeoff exists between antibody evasion and fitness.

Hosts: Nels Elde and Vincent Racaniello

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SARS-CoV-2 evolution during chronic infection (Nat Med)
Letters read on TWiEVO 79
Time stamps by Jolene. Thanks!

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TWiEVO 79: When the immune system is away, SARS-CoV-2 will play