Well Beyond 40 Unpacking GLP-1s: A New Approach to Weight Health with Ashley Koff
Feb 11, 2026
Ashley Koff, RD, founder of The Better Nutrition Program and author of Your Best Shot, shares her shift from dieting to a weight-health ecosystem. She explores how ultra-processed foods and under-fueling harm hormones and metabolism. The conversation covers what GLP-1s do, their effects on digestion and muscle, and how to use or wean from them responsibly.
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From Selling Sugary Cereals To Healing Digestion
- Ashley Koff describes her early career selling sugary cereals and then hitting rock bottom with extreme cleanses and dieting.
- A gastroenterologist told her the problem was missing resources in her body, which redirected her career to nutrition and healing digestion.
Weight Health Ecosystem Beats Weight Obsession
- Ashley reframes the body as a 'weight health ecosystem' driven by weight-health hormones like GLP-1, GIP, PYY, and CCK.
- Optimizing these hormones, not just chasing weight loss, helps preserve muscle, bone, metabolism, and overall function.
Ultra-Processed Foods Undermine Nutrient Resilience
- Ultra-processed foods undermine satiety and leave bodies chronically under-resourced in essential nutrients.
- The problem is often what those foods lack, not just what they contain, so modern diets reduce metabolic resilience.
