The Curbsiders Internal Medicine Podcast

Addiction Medicine Series #1 Methadone for OUD w/Dr. Ruth Potee

17 snips
Jul 7, 2022
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ANECDOTE

Fentanyl's Devastating Effects

  • Dr. Ruth Potee described fentanyl as 'garbage' that forces people to use repeatedly just to feel normal.
  • She emphasized the harm from frequent injections: more overdoses, infections, and hospitalizations.
ADVICE

Use The 72‑Hour Bridging Rule

  • The DEA's 72‑hour rule allows ED or hospital pharmacies to dispense methadone to outpatients for up to 72 hours while arranging OTP follow‑up.
  • Use this to bridge patients from ED to clinics when immediate transfer isn't possible.
ADVICE

Therapeutic Dose Range And Caution

  • Expect most patients to stabilize between ~80–120 mg methadone, though individual needs vary widely.
  • Slow increments when you reach ~60 mg because methadone accumulates with a long half‑life.
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