Brains and Gains with Dr. David Maconi James Krieger on Volume Study Controversy, Testosterone, Insulin
Feb 24, 2019
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Pre-Specified Stats Prevent Accusations
- Statistical choices must be pre-specified and transparent to avoid accusations of p-hacking or gaming results.
- Krieger used pre-decided frequentist and Bayesian analyses and argues the volume results were robust across methods and visually clear on graphs.
Open Data Cuts Skepticism In Research
- Research transparency like sharing public datasets reduces distrust from p-hacking and data dredging.
- Krieger supports open data and notes pre-registering analyses helps others replicate and check work.
Muscle Thickness May Include Swelling
- Ultrasound muscle thickness can't separate true protein-driven hypertrophy from fluid-related swelling.
- The study measured 48–72 hours post-session; swelling can't be fully ruled out, but a prior military replication measured up to 5 days and found similar patterns.