

Brains and Gains with Dr. David Maconi
Dr. David Maconi
On the Brains and Gains podcast, Dr. David Maconi discusses all things exercise science, nutrition, health, and personal development. Every week, Dr. Maconi invites health experts and thought leaders to share their expertise. Each episode ends with a charity donation to the charity of the guest's choice.
Episodes
Mentioned books

Mar 21, 2026 • 1h 19min
Data Driven Strength - Self-Experimentation, Response Differences, Diminishing Returns
Josh, co-founder of Data Driven Strength and PhD candidate in applied coaching science, and Zach, researcher/coach with doctoral work in exercise science, discuss self-experimentation and why single-person tests can mislead. They explore baseline versus response differences, challenge the idea of stable "volume responders," and debate diminishing returns, specialization phases, and how energy flux and lifestyle shape real-world outcomes.

Mar 13, 2026 • 1h
Aaron Straker + Bryan Boorstein -- Hyper-responders, Back to Bro Splits, PEDs Too Early
0:00- Intro 0:30- Bryan’s journey testing glucose levels 8:30- My home OGTT test and more on glucose 11:50- Aaron’s glucose monitoring journey 14:30- Bryan’s bro split 17:30- Specialization routine 20:00- Aaron’s volume 23:00- Supplements 26:45- TRT for increasing dopamine baseline 43:30- Using PEDs early in your training career 52:30- Hyper-responders to PEDs

Feb 21, 2026 • 49min
Dr. Jason Tanoory - Sleep Routines, Life Success While Staying Fit, Powerlifting With Age
Dr. Jason Tanoory, a dentist and competitive powerlifter/bodybuilder who balances career and family while training hard. He discusses aging in strength sports, training adjustments for longevity, building a massive home gym for consistency, strict sleep routines and journaling, and experimenting carefully with peptides and metabolic tools.

Feb 14, 2026 • 1h 18min
Abel Csabai - Specialization Update, Plastic Surgery, AI Implementation
Abel Csabai, fitness content creator and coach known for evidence-informed training and dieting takes on plastic surgery norms, why people moralize appearance changes, and how dopamine reshapes pleasure and motivation. He then explores rapid AI impacts on fitness and medicine, who might be AI-proof, and practical coach-client AI dynamics. The conversation closes with Abel’s current high-frequency training and dieting update.

Nov 29, 2025 • 1h 28min
Steve Hall Q&A - Solomon Nelson Videos, Shifting Away From RP Training, Neuromechanical Matching
0:00- Intro 1:00- Revive Stronger podcast 3:20- Solomon Nelson videos / Mike Israetel controversy 12:00- Being influenced by others’ training 14:30- What led Steve to shifting away from RP style training? 31:30- Steve’s volume 44:00- Steve’s progress 48:00- Proper way to warm up 53:30- Advice for a 16 year old to progress 58:00- Given metabolic research, what’s the highest you’d push step count to? 1:01:15- MUI Goku vs Ultra Ego Vegeta 1:03:20- Neuromechanical matching and muscle leverages 1:09:30- Theory that you have to hit each region of the muscle or it atrophies within 4 days 1:10:50- Why Steve uses a limited ROM 1:14:00- Fake natties in competition 1:17:30- Thoughts on a 4 day upper/lower/push/pull split

Nov 15, 2025 • 1h 29min
Dr. Eric Helms - HUGE Gains In One Season, High Volume, Contest Prep Surprises
0:00- Intro 1:00- AI in education 4:00- Eric’s latest bodybuilding show 12:00- Objective measurements 14:00- Does young training influence specific development later in life? 26:00- Strategy for upcoming shows 30:00- Problems during prep 43:00- Tracking during prep 55:00- Specific changes for the next two shows 1:08:00- Training changes from last off season to this off season and prep 1:23:30- Where did Eric’s progress really come from? 1:28:00- Where to find Eric

Nov 1, 2025 • 1h 12min
Alberto Nunez Q&A - Optimizing 2-3 Days of Training, Tracking Cheat Meals, Proper Exercise Selection
0:00- Intro 1:30- Alberto contest updates 14:30- How to do proper exercise selection for back training 17:30- How to accurately track cheats during a diet 29:45- Are knee sleeves helpful for bodybuilding? 31:45- What are the biggest changes you’ve made prepping as a father? 40:25- How to optimize training when limited to 2-3 days per week 47:00- When you’re tired during prep, would you add refeed days? 52:15- Best way to bring up lagging arms 1:04:30- Who are your go to sources of information

Oct 18, 2025 • 1h 31min
Basement Bodybuilding Q&A - What If You Lost All Gains, 19 Inch Arms, Staying Shredded
0:00- Intro 0:30- Motivation 10:00- Getting shredded and maintaining a shredded state 12:00- Artificial sweeteners 19:30- What is the best way to eliminate hip shift during squats? 22:30- Getting stronger but not bigger, what is the cause? 25:30- Growing home gym space, better than commercial gyms? 35:15- How big should one expect to be for a certain height 36:15- How many meals per day and how many times do you train per week? 45:30- Atlaspowershrugged trolling 46:00- Best lift named after someone 50:00- Can I reach an advanced physique without being obsessed with lifting? 55:50- Is there any benefit to bulking beyond 15% body fat? 1:00:40- If you lost all of your gains, what would you do to get jacked again? 1:04:45- Minimum number of sets per week to grow muscle? 1:06:45- Do you find wide grip pulldowns to be worth it for lats? 1:09:00- Nausea during training 1:10:30- When is the road to 19” arms? 1:16:45- How to program a good bodybuilding program if you have 3 days to train? 1:21:00- How do you program brachialis training in your program?

12 snips
Oct 4, 2025 • 1h 29min
Mario Tomic Q&A - High Dose Creatine, Knowing You're 10%, Genetic Variation
Mario Tomic, a fitness coach and content creator known for his evidence-based approach, dives into fascinating insights on high-dose creatine, revealing its potential boost in mental energy and gym performance. He discusses how to accurately gauge reaching 10% body fat using various methods, and when faced with weight loss plateaus, he shares critical strategies. Delving into genetics, Mario emphasizes their role in fat loss and muscle gain variability. He also highlights the importance of progressive overload to avoid injuries during training.

4 snips
Sep 27, 2025 • 1h 3min
Geoffrey Verity Schofield Q&A (Pt 2): Paul Carter, Lyle McDonald, Beyond Failure Training
Geoffrey Verity Schofield, a seasoned lifter and coach, shares his profound insights on training techniques and philosophies. He tackles the complexities of beyond-failure training and how to mitigate injury risks. Geoff also discusses the importance of not getting too fixated on the logbook and offers strategies for advanced naturals to maintain leanness without sacrificing progress. Delving into disagreements with Lyle McDonald, he challenges common assumptions about muscle growth and underscores the significance of programming variations.


