Your CMO Mentor

How to build a data-driven marketing strategy

Dec 18, 2025
Jamie Domenici, CMO at Klaviyo, brings a wealth of experience in data-driven marketing and team dynamics. She discusses how to align marketing strategies with company goals to avoid becoming spreadsheet-obsessed. Jamie emphasizes the importance of storytelling, adapting to always-on momentum alongside major launches, and the power of experimentation. She shares insights on navigating gut instincts versus data, avoiding common strategic pitfalls, and fostering a culture where failure is embraced as part of the learning process.
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ANECDOTE

A Keynote That Forced Better Storytelling

  • Jamie bombed a Salesforce keynote and then worked with a coach to improve storytelling.
  • The coach taught her to open with a strong first sentence to hook the audience.
ADVICE

Rotate Roles To Build Versatility

  • Early in your career, do every job you can to build a broad marketing skillset.
  • Seek uncomfortable roles frequently to find strengths and learn what to hand off later.
ADVICE

Make Sales Your First Marketing Partner

  • B2B marketers should partner tightly with sales and share the same targets.
  • If marketing and sales have different targets you've already failed, so align immediately.
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