The Curbsiders Internal Medicine Podcast

#426 Breast Cancer for the PCP With Dr Sandhya Pruthi

Feb 12, 2024
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ANECDOTE

Mentor Opened Doors To Prevention Work

  • Sandhya Pruthi described starting in a Mayo breast clinic when it opened and mentors nudged her toward research roles.
  • That mentorship led her to run prevention trials and expand beyond clinical care to avoid burnout.
ADVICE

Prepare Patients Before Biopsy

  • Tell patients biopsy results in person when possible and prepare them beforehand about possible outcomes.
  • Before biopsy, explain it could show benign changes, atypia, or DCIS to lessen shock if cancer is found.
INSIGHT

Active Surveillance For Select DCIS

  • Active surveillance for low/intermediate grade, ER+ DCIS was tested in the COMET trial versus standard treatment.
  • Some lesions remain stable on surveillance, suggesting biology-driven de-escalation may be possible pending trial results.
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