Huberman Lab

Restore Youthfulness & Vitality to the Aging Brain & Body | Dr. Tony Wyss-Coray

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Feb 23, 2026
Dr. Tony Wyss-Coray, a Stanford neurology professor studying blood-borne factors that influence aging. He discusses young-blood proteins and plasma factors that rejuvenate organs. They explore how exercise, sunlight and fasting change blood signals. He covers organ-specific aging, blood biomarkers for biological age, and risks of unproven stem-cell therapies.
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Young Blood Reprograms Aging Brains

  • Young blood contains factors that reactivate stem cells, reduce inflammation, and increase neuronal activity.
  • Tony Wyss-Coray reports these changes translated into improved memory in aged mice after young-factor exposure.

Test Plasma Therapies Rigorously

  • Therapeutic plasma exchange and pooled plasma fractions are being tested clinically for neurodegenerative disease.
  • Wyss-Coray suggests rigorous, controlled trials are needed to confirm efficacy in humans.

Organs Age On Different Timelines

  • Organs and even cell types age at different rates and produce distinct blood signatures.
  • Wyss-Coray explains organ-specific 'age gaps' predict future organ-specific disease risk.
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