Vitality Versus Longevity Trade-offs

They discuss antagonistic pleiotropy, hormones like IGF-1, and balancing youthful vitality with potential lifespan costs.

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Episode notes

Dr. Tony Wyss-Coray, PhD, is a professor of neurology at Stanford School of Medicine and Director of the Phil and Penny Knight Initiative for Brain Resilience who is discovering factors present in young blood and in exercised blood that can improve brain, heart, and other organ health. We discuss how different organs age at different rates and how to accurately measure biological aging. We also discuss the specific proteins found in blood when we are young and that are increased by things such as exercise, sunlight exposure, short-term fasting, specific foods, and social connection that can significantly increase vitality, restore youthful functioning of the brain and body, and potentially increase lifespan.

Read the episode show notes at hubermanlab.com.

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Timestamps

(00:00:00) Tony Wyss-Coray

(00:03:00) Young vs Old Animals, Age-Related Disease

(00:06:35) Blood Biomarkers, Young vs Old Humans, Alzheimer's Disease

(00:12:50) Sponsors: David & LMNT