Modern Wisdom #066 - Professor David Sinclair - Can Humans Live For 1000 Years?
Apr 22, 2019
In this engaging discussion, Professor David Sinclair, a Harvard geneticist and co-Director of the Paul Glenn Centre, unpacks the fascinating science of aging. He explores how stabilizing the epigenetic landscape could potentially extend human life to 1,000 years. Sinclair shares his personal strategies for longevity, including fasting and the role of Sirtuins and NAD in health promotion. The conversation also dives into ethical implications of longevity research and the societal impacts of increased lifespan, making for a thought-provoking listen.
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Calorie Restriction for Longevity
- Eat less to extend lifespan, as shown in various species.
- This activates longevity pathways, regardless of specific diet.
Intermittent Fasting and Metformin
- Practice intermittent fasting by skipping breakfast and having a late lunch.
- Consider metformin to lower blood glucose and curb hunger.
How Calorie Restriction Works
- Calorie restriction boosts NAD levels, activating sirtuin genes.
- Sirtuins control gene expression and maintain youthfulness.
