The Bayesian Conspiracy

48 – Cryonics 2 – Lacuna Matata (with Robert McIntyre)

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Nov 22, 2017
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INSIGHT

Information, Not Alive Function, Is The Goal

  • Brain preservation aims to preserve the information (connectome) rather than metabolic function.
  • Missing structural data (lacunae) makes reconstruction impossible even with advanced imaging.
INSIGHT

Synapses Encode Memories

  • Synaptic connectivity (the connectome) is the leading hypothesis for memory storage.
  • Preserving synapse locations and strengths is essential to keep memories recoverable.
ANECDOTE

Alcor Case With 17-Hour Delay

  • Robert McIntyre recounts Alcor's Robert Whittaker case with a 17-hour delay before preservation began.
  • He highlights that prolonged warm ischemia before perfusion is very bad for preserving synapses.
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