Project Swagger with Robin Arzón Mark Cuban On Aging Backwards, AI, and... Clams?!
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Mar 18, 2026 
Mark Cuban, billionaire entrepreneur and Mavericks owner, shares quick takes on longevity, fitness routines, and hustle. He talks about tracking health with blood panels, using AI as a practical tool, and rewiring habits like sleep and workouts. He also explains lessons learned from elite athletes and his surprising high-protein lunch hack.
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Prioritize Learning Your Body's Changing Signals
- Learn your body because aging changes how it responds to inputs like workouts, food, and supplements.
- Mark Cuban measures reactions over time and adjusts timing and combinations to optimize results using data and curiosity.
Use Frequent Blood Panels Paired With AI Guidance
- Test biomarkers regularly and use AI to translate blood results into actionable changes.
- Cuban gets blood panels every 3–6 months and asks Claude how to improve specific markers and timing of supplements.
Schedule Supplements To Avoid Nutrient Conflicts
- Space conflicting supplements and meds to avoid interference and boost performance.
- Example: Cuban discovered iron and calcium conflict, adjusted timing, and saw workout improvements in ~45 days.