Knowledge Cast by Enterprise Knowledge TJ Hsu - Director of R&D Knowledge Management at Amgen
Mar 3, 2026
TJ Hsu, Director of R&D Knowledge Management at Amgen and AI/knowledge services veteran, shares how to turn individual smarts into collective intelligence. He discusses targeting key personas, building curated knowledge centers and Copilot-style experiences, cleaning content for trustworthy AI, and using knowledge graphs, experts, and simulations to speed research and improve decision making.
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Target Linchpin Roles Not Everyone
- Prioritize by deeply understanding key roles and target linchpin personas instead of trying to serve everyone.
- TJ uses human-centered design to focus the small KM team on high-impact R&D, development, and medical roles and their in‑flow needs.
Make KM Relevant To Leadership Priorities
- Map KM work to leadership's prioritized agenda so KM is relevant and funding-friendly.
- Solve high‑value business problems and create enterprise patterns so pilots can scale across functions.
Quick Win By Reworking IVDR Compliance Training
- TJ established credibility at Amgen by converting heavy LMS compliance training on the EU IVDR into concise, role‑specific knowledge centers.
- He created topical pages plus a Copilot chatbot and pushed targeted guidance to clinical trial teams before vendor engagements.