The "What is Money?" Show Peptides, Fasting, and the Future of Longevity w/ Miguel & Carlos
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Mar 13, 2026 Intranasal nootropics and rapid nose-to-brain delivery for flow and cognition. Deep dives on peptides as biological signals and seasonal cycling of growth and repair. Fasting, autophagy, fat adaptation, and practical 72-hour fast strategies. Mitochondrial fixes, sleep recovery, regenerative topicals, and targeted protocols for brain repair and immune resilience.
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Nose To Brain Nootropics Work Via Olfactory Signaling
- Intranasal neuroregulatory peptides like C-Max and C-Lanx use the nose-to-brain olfactory pathway to boost BDNF, neuroplasticity, and cognition without crossing the blood-brain barrier.
- Miguel and Carlos describe 80µg nasal doses, hourly low-dose pulsing, and anecdotal flow-state effects like improved skateboarding coordination after ~750µg.
Don't Signal Growth When The Body Isn't Ready
- Respect signaling, pathways and timing: send peptide signals only when the receptor pathway and metabolic context (inflammation, liver, mitochondria) are ready to receive them.
- Carlos warns against stacking haphazardly in inflamed or insulin-resistant patients and uses clinical observation to guide sequencing.
Quarterly 72 Hour Pit Stops For Autophagy
- Cycle growth (mTOR/IGF-1) and repair (AMPK, sirtuins, NRF2) pathways seasonally and with short pit-stops to avoid chronic mTOR-driven damage.
- They recommend quarterly 72-hour fasts (water + salt, no amino acids) to induce autophagy and preserve muscle if resting.