Pillow Talks

E245: What It’s Really Like to Start TRT: Xander’s Testosterone Journey

Jan 29, 2026
A personal testosterone journey that covers why low energy became impossible to ignore and how sobriety revealed a new baseline. They walk through functional medicine testing, confusing “normal” ranges, and lifestyle tweaks that fell short. Treatment paths are compared—creams, Clomid, injections—and the realities of injections, costs, fertility risks, and mood and body changes are discussed.
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INSIGHT

T To E Ratio Matters More Than T Alone

  • Adding testosterone often raises estrogen via aromatization, so balance matters more than raw T.
  • Regular blood tests and possible aromatase inhibitors are essential to maintain a healthy T:E ratio.
ADVICE

Manage Estrogen With Careful Dosing

  • Do discuss and monitor estrogen suppression using aromatase inhibitors like anastrozole if tests show high estrogen.
  • Use precise dosing and lab follow-ups because common pills require quarter-doses for men.
ANECDOTE

Found Personal Optimal Range

  • Xander found his ideal total T around 900–1,000 ng/dL where benefits outweighed estrogen rise.
  • Overshooting T increased estrogen disproportionately and negated positives.
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