
The Human Upgrade: Biohacking for Longevity & Performance How Your Biomes Drive Custom Food & Supplement Solutions – Naveen Jain : 1005
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Dec 16, 2022 Naveen Jain, an entrepreneur and philanthropist, discusses the fascinating connection between the oral microbiome and overall health. He reveals how Viome's AI-driven platform customizes food and supplement recommendations based on personal biome analysis. The conversation highlights the importance of gut health in longevity, personalized nutrition, and how factors like genetics influence dietary needs. Jain also addresses myths about supplements and introduces innovations in saliva testing for oral health, emphasizing tailored approaches for optimal well-being.
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Alzheimer's Trigger
- Alzheimer's may be triggered by C. pneumoniae binding to the APOE4 gene, not solely by the gene itself.
- External factors influence gene expression, exemplified by elephants with multiple APOE4 copies having good memory.
Personalized Nutrition
- Adjust food intake based on gut microbiome analysis to minimize negative byproducts like sulfide.
- Avoid universal healthy food recommendations; personalize diets based on individual gut microbiome needs.
Gene Expression Measurement
- Viome analyzes mRNA and non-coding RNA to understand gene expression changes influenced by epigenetics.
- Epigenetics, influenced by factors like methylation, affects gene expression without altering the DNA sequence itself.

