The Gillett Health Podcast Scientifically Dismantling Biohacking, Longevity, & Peptides
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Mar 31, 2025 Jim Lavalle, an internationally recognized clinical pharmacist and author, dives into biohacking, longevity, and peptides. He discusses the pitfalls of overtraining and its effects on glucose metabolism. Jim sheds light on the complexities of hormone therapies, emphasizing the significance of hormone balance in aging. He critiques current weight loss strategies involving GLP-1 medications while advocating for lifestyle changes and personal accountability. Lastly, he highlights the importance of quality control in peptide production to ensure safety and efficacy.
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Hormone Usage Prevalence
- Consider environmental estrogens and other hormone-mimicking compounds when assessing hormone levels.
- Over 50% of the US population has likely tried some form of hormone, including oral contraceptives and SARMs.
Hormone Delivery Methods
- Estradiol cipionate is easier to maintain steady levels compared to valerate.
- Consider a baseline plus pulsatile hormone delivery for circadian rhythm.
Testosterone Absorption
- Orally absorbed, lymphatically delivered testosterone does not require fat intake for optimal absorption.
- This method utilizes micelles to bypass the need for fat.