From First Principles Dark Galaxies, Fuzzy Dark Matter, and an Alzheimer’s Breakthrough (EP. 28)
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Mar 4, 2026 A deep-sky mystery about a Perseus Cluster object that could be a nearly pure dark matter halo and a testbed for missing-satellites, cusp–core debates, and fuzzy dark matter. A biomedical thread traces how exercise-linked liver enzyme GPLD1 may repair the blood–brain barrier and how an oral TNAP inhibitor mimics the protective effect in mice. Plus quick rundowns on Rubin alerts, AI magnet discovery, Easter Island climate, and the Boba–Kiki effect.
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Fuzzy Dark Matter Could Explain Cores
- 'Fuzzy dark matter' models predict galaxy‑scale quantum pressure if particle mass is extremely low, producing cores instead of cusps.
- Krishna notes de Broglie wavelengths for ~10^-22 eV particles span hundreds of light years, enabling a Bose‑Einstein–like core.
Vera Rubin Turned Nightly Sky Into Real Time Alerts
- The Vera Rubin Observatory's real‑time alert engine is now live and produced ~800,000 alerts on night one, scaling toward millions per night.
- Lester Nare and Krishna highlight this will shift astronomy from targeted telescope time to wide transient discovery and AI triage.
AI Accelerates Permanent Magnet Discovery
- AI mined thousands of materials papers to build a searchable database of ~67,000 compounds and flagged 25 high‑temperature permanent magnet candidates.
- Krishna and Lester compare this to AlphaFold as an acceleration of materials discovery pipelines.