Episode #263: Dr. Greg Kelly: NAD+ in Aging: Effects on Longevity + How it Works

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Aug 30, 2024

Dr. Greg Kelly, a leading expert and author focused on NAD+ and aging, shares fascinating insights into the role of this vital molecule in longevity. He explains how NAD+ supports cellular health and its crucial role in energy production and DNA repair. The discussion includes the timing of NAD+ supplementation for optimal metabolic benefits and explores the effectiveness of NAD+ infusions. Additionally, Dr. Kelly highlights the relationship between NAD+ levels and gut health, emphasizing the importance of a balanced approach to supplementation.

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INSIGHT

NAD+ Redox Roles

NAD+ acts as a redox molecule, essential for carrying electrons to mitochondria for ATP production.
NAD+ exists in various forms (NAD+, NADH, NADP+, NADPH) with specific redox functions.

INSIGHT

NAD+ and Aging

Historically, NAD+'s redox role was its primary function.
A healthy NAD+/NADH ratio is crucial, with NAD+ levels declining and NADH rising with age.

INSIGHT

NAD+ Consumption Roles

NAD+'s role in longevity stems from its consumption by sirtuins, PARPs, and CD38.
Sirtuins, fueled by NAD+, are involved in cellular stress response and repair.

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Have you ever wondered why some people seem to age more gracefully than others? The answer might lie in a molecule called NAD+. In this podcast episode, we dive deep into the world of NAD+ with Dr. Greg Kelly, a leading expert in the field.

We discuss a comprehensive overview of NAD+, its role in longevity and cellular resilience, and the importance of timing when supplementing it. We also dive into the effectiveness of NAD+ infusions, the importance of NAD+ resources in cellular response to stress, and Qualia Life's NAD+ supplement.

Gregory Kelly is Director of Product Development at Neurohacker Collective, a naturopathic physician (N.D.), and the author of the book Shape Shift. He was the editor of the journal Alternative Medicine Review and has been an instructor at the University of Bridgeport in the College of Naturopathic Medicine, where he taught classes in Advanced Clinical Nutrition, Counseling Skills, and Doctor-Patient Relationships. Dr. Kelly has published hundreds of articles on natural medicine and nutrition contributed three chapters to the Textbook of Natural Medicine, and has more than 30 journal articles indexed on Pubmed.

Want to try Qualia NAD+? Visit http://www.qualialife.com/longevity and use code LONGEVITY for 15% off your order.

Thank you to our sponsors for making this episode possible:

Stemregen: Save 15% on your first order at http://www.stemregen.co/nat, use code NAT15

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Find more from Dr. Greg Kelly:

Website: https://www.qualialife.com/people/greg-kelly

Instagram: @qualialife

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YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ

Join Nat's Membership Community: https://www.natniddam.com/bsp-community

Instagram: https://www.instagram.com/nathalieniddam/

Website: www.NatNiddam.com

Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance

What We Discuss:

03:01 The History and Origins of NAD+

10:12 NR vs. NMN: Comparing NAD+ Precursors

15:03 The Importance of Timing in NAD+ Supplementation

24:57 Exploring NAD+ Infusions: Benefits and Risks

37:50 The Effectiveness of NAD+ Infusions

45:21 NAD's Role in Longevity and Cellular Resilience

51:46 The Importance of NAD+ Resources in Cellular Response to Stress

56:23 The Salvage Pathway and ATP Production

01:04:25 Quality of Life's NAD+ Supplement: Supporting NAD+ Levels and ATP Production