
The Human Upgrade: Biohacking for Longevity & Performance #5: How To Quantify Fatigue Like Never Before
Sep 19, 2011
Rick Green, co-creator of the groundbreaking Fatigue Biomarker Test and founder of Hyperion Biotechnology, joins John Kalns, an expert in peptide measurement. Together, they unveil the first objective test that measures fatigue through salivary peptides, a game-changer for anyone from athletes to busy professionals. They delve into how this innovative test helps gauge stress levels, optimize health interventions, and manage fatigue intelligently, allowing listeners to understand when they might be pushing their limits.
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Simple Saliva Collection Method
- To take the fatigue test, you simply spit about two tablespoons of saliva in a tube and mail it in.
- The test uses advanced liquid chromatography mass spectrometry for accurate analysis.
Future Rapid At-Home Testing
- Future versions of the test aim to offer quick results similar to a pregnancy test using antibodies.
- This could reduce wait times from days to minutes, making fatigue measurement accessible at home.
Understanding Fatigue Complexity
- Fatigue is complex and linked to actual performance beyond self-perception.
- The biomarker correlates with performance decline and subjective fatigue but is more objective and reliable.


