Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+ Ep. 589 “Your Labs Are Lying to You!” – The 3 Essential Thyroid Markers Your Doctor Isn’t Checking with Dr. Amie Hornaman | Menopause, Perimenopause & Thyroid
May 6, 2026
Dr. Amie Hornaman, physician and founder of the Advanced Thyroid and Hormone Clinic, aka The Thyroid Fixer. They dive into the hidden thyroid epidemic and why many women are misdiagnosed. Topics include reverse T3 and stress, mitochondrial energy and thyroid conversion, gut and digestion links, oral contraceptives and thyroid risk, environmental toxins, NDT and iodine cautions, plus three practical lifestyle strategies.
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Thyroid Dysfunction Is Widely Underdiagnosed
- Hypothyroidism is massively underdiagnosed because standard lab ranges miss suboptimal function.
- Dr. Amie Hornaman argues true prevalence may be closer to 10–12% or even 1 in 4 due to medical gaslighting and narrow TSH-based diagnosis.
Reverse T3 Puts The Body In Survival Mode
- Reverse T3 is a survival mechanism that rises in stress and redirects energy away from metabolism.
- Elevated reverse T3 in everyday life causes fatigue, weight gain resistance, and sluggish cognition by blocking active T3 action.
Many Factors Block T4 To T3 Conversion
- T4 can convert to active T3 or to reverse T3; many factors shift conversion toward reverse T3.
- Estrogen dominance, insulin resistance, nutrient deficiencies, chronic stress, infections, and DIO1/DIO2 SNPs impair T4→T3 conversion.
