Mayo Clinic on Nutrition

Perimenopause, PMS, and PCOS: All About the Period

Dec 2, 2025
Danielle Cahalan, a lead dietitian specializing in women's health, dives into the complexities of menstrual cycles, covering everything from cycle syncing to perimenopause. She discusses how nutritional needs shift across phases and the physiological reasons behind cravings and appetite changes. Danielle shares insights on managing PCOS and endometriosis with diet and offers practical tips on hydration, exercise, and addressing misconceptions related to hormone replacement therapy. Lastly, she highlights the importance of reliable resources for women's health.
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ADVICE

Use Strength Training And Protein In Midlife

  • In perimenopause, focus on blood sugar control, resistance training, and higher protein to preserve muscle.
  • Use accessible strength options like weighted vests, bands, or Reformer Pilates if barbell lifting feels intimidating.
INSIGHT

Midlife Fat Gain Is Multifactorial

  • Weight gain in midlife often reflects insulin resistance and the body's attempt to produce estrogen via fat stores.
  • Body composition (muscle vs fat) matters more than scale weight for health and appearance.
ADVICE

Consider HRT With Medical Guidance

  • Discuss hormone replacement therapy (HRT) with your provider; it can improve mental health, vitality, and biomarkers for eligible women.
  • Screen for contraindications like reproductive cancers and medication interactions before starting HRT.
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