The Curbsiders Internal Medicine Podcast #428 DIGEST: DVT prophylaxis in patients with cancer, anticoagulation in subclinical AFib, steroids in COPD exacerbations, breast cancer genetic testing guidelines, and at-home STI testing
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Feb 26, 2024 
Topics include DVT prophylaxis in cancer patients, anticoagulation in subclinical atrial fibrillation, steroids in COPD exacerbations, genetic testing guidelines for breast cancer, and at-home STI testing. Dive into medical updates and trial discussions with a touch of humor.
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Lab-Guided VTE Prophylaxis Helps High-Risk Cancer Patients
- Targeted thromboprophylaxis using D-dimer and fibrinogen stratified high-risk cancer outpatients reduces thromboembolism rates.
- Prophylaxis brought high-risk rates down to low-risk levels and showed a survival signal in this trial.
Outpatient Prophylaxis Faces Uptake And Duration Questions
- Outpatient thromboprophylaxis remains uncommon despite guideline suggestions and evidence.
- Practical questions remain about who manages it and optimal duration during chemotherapy.
Use Eosinophils To Tailor COPD Steroids
- Consider using peripheral eosinophil counts to guide systemic steroid use during COPD exacerbations.
- Eosinophil-guided therapy was noninferior to treating everyone and reduced steroid exposure.