LONGEVITY with Nathalie Niddam #428: Poop, Peptides & The Power of Microbiome | The Secret Longevity Organ With Dr. Grace Liu
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Apr 10, 2026 Dr. Grace Liu, microbiome scientist and founder of The Gut Institute, aka the Gut Goddess, explains why poop reveals your aging biology. She covers fecal transplants, peptides and regenerative research. Conversations include butyrate from resistant starch, ancestral cooking, microbiome diversity loss, risks of DIY fixes, and practical weeding, seeding and feeding strategies.
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Early Microbiome Trains Immunity And Brain
- Gut composition shapes immune development and brain wiring from birth, affecting autism, ADHD, anxiety and depression risk.
- Disruptions like C-section, formula, antibiotics and hyper-clean environments impede this early microbial education.
Prefer Cooked Cooled Resistant Starches
- Feed butyrate-producing microbes with cooked-and-cooled resistant starches (type 3) rather than raw starch powders.
- Grace cautions raw starch can feed yeast and E. coli and flare autoimmunity in susceptible people.
Reintroduce Starches Gradually With Testing
- Rebuild carb-digesting bacteria slowly: start with small bites of ancestral starches and use targeted probiotics to restore the six key taxa.
- Track microbiome (e.g., ViTRaCT) and add lorazotide to tighten gut when needed.