The Curbsiders Internal Medicine Podcast

#350 Rapid Response Series: Acute Hypoxemia

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Aug 15, 2022
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INSIGHT

Hypoxemia Versus Hypoxia

  • Hypoxemia is low oxygen in the blood and differs from hypoxia, which is low tissue oxygen.
  • Pulse oximetry measures saturation while blood gas measures dissolved PaO2, giving different but complementary data.
INSIGHT

Oxygen Content And Delivery Matter

  • Oxygen content depends mainly on hemoglobin and saturation, not just saturation alone.
  • Oxygen delivery equals content times cardiac output, so anemia or low output can cause tissue hypoxia despite normal sats.
INSIGHT

How Pulse Oximetry Works

  • A pulse oximeter shines red and infrared light through skin to estimate hemoglobin saturation.
  • It reports saturation indirectly while arterial blood gas directly measures PaO2 (dissolved oxygen).
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