
Biohacking Beauty: The Anti-Aging Skincare Podcast Dr. Doris Day: Reverse Skin Aging By Fixing Inflammation
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Nov 26, 2025 Dr. Doris Day, a board-certified dermatologist and expert in longevity, combines her medical training with health optimization to tackle skin aging. She explores the deep connection between skin health and overall wellness, emphasizing that reducing skin inflammation can lower systemic inflammation too. Doris discusses the innovative SoftWave treatment for collagen maintenance, introduces the selective mTORC1 inhibitor RLX201 for rejuvenation, and encourages an internal health focus for youthful skin. Her insights showcase that beautiful skin isn't just achievable, it's sustainable at any age!
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Prejuvenation: Treat Only What Needs It
- Use noninvasive tools selectively and avoid unnecessary treatments on perfect young skin.
- Combine good skincare, sun protection, nutrition, and occasional device treatments like SoftWave for true prejuvenation.
Pick Safe Collagen-Building Devices
- Choose devices with proven safety and predictable collagen-building profiles to avoid fibrosis and fat loss.
- SoftWave delivers ultrasound into the skin to tighten and build collagen without scarring when used appropriately.
Selective mTOR1 Blockers Rewind Fibroblasts
- Selective mTORC1 inhibitors (RLX201/ReQueue) can reverse fibroblast aging and prevent senescence from over-stimulation.
- Pairing these molecules with growth factors or exosomes may enable skin 'aging reversal' without exhausting repair cells.



