The Curbsiders Internal Medicine Podcast

#332 Inpatient Covid Management with Dr. Nathan Erdmann

13 snips
May 2, 2022
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ADVICE

Trend Inflammatory Markers, Don’t Rely On One Value

  • Use a panel of inflammatory markers (CRP, ferritin, d-dimer, Ct when available) to monitor trajectory, not as sole decision points.
  • Repeat markers over 48–72 hours to detect rising trends that warrant escalation.
ADVICE

Start Remdesivir And Steroids With Hypoxia

  • For patients who develop oxygen requirement, start antiviral therapy (remdesivir) and give corticosteroids for respiratory involvement.
  • Treat the viral replication phase and inflammatory lung disease concurrently when respiratory signs appear.
INSIGHT

Tailor Remdesivir Duration To Immune Status

  • Remdesivir is typically used as a five-day course in most hospitalized patients; extend to ten days for significant immunosuppression.
  • Duration decisions should factor in immune status and clinical trajectory.
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