the goop podcast Therapeutic Plasma Exchange: The Future of Detoxification
Feb 10, 2026
Dr. Paul Savage, integrative medicine physician and founder of MD Lifespan, who pivoted from ER care to longevity and advanced detox, discusses therapeutic plasma exchange. He explains how plasma carries toxins, why modern exposures overwhelm clearance, and a protocol combining serial TPE with supportive nutrients. The conversation covers reported lab reductions, symptom improvements, safety considerations, costs, and practical toxin-avoidance tips.
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Toxins Fuel Chronic Immune Confusion
- Antibodies form against novel toxins and can cause chronic immune activation and cross-reactivity.
- Savage links rising chronic inflammation to immune responses against persistent environmental chemicals.
A Balcony Epiphany Led To TPE Focus
- Dr. Paul Savage describes a personal epiphany reading papers linking plasma exchange to improved aging and cognition.
- He cried on a balcony in Brazil when he realized serial TPE could address toxin-related illness.
Pair TPE With Supplements And Avoidance
- Combine serial TPE with targeted nutrients, IV support, and home avoidance measures for best results.
- Dr. Paul Savage requires patients reduce household exposures before starting to maximize benefits.
