Nels and Vincent continue their discussion of SARS-CoV-2 evolution, with a report that the coronavirus proofreading enzyme stimulates RNA recombination, and debunking the conclusion that a change in the viral spike glycoprotein is associated with increased human to human transmission.

Hosts: Nels Elde and Vincent Racaniello

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CoV proofreading enzyme stimulates recombination (bioRxiv)
CoV spike mutation pipeline (bioRxiv)
Issues with CoV sequencing data (virological.org)
Bill Hanage on selection vs bottleneck (threader.app)
Image credit
Time stamps by Jolene. Thanks!

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TWiEVO 55: Coronavirus evolution from soup to nuts