Biohacking Beauty: The Anti-Aging Skincare Podcast

This is Why Your NAD+ Routine Isn’t Reaching Your Skin + The Fix

Aug 27, 2025

Discover why your skincare might be falling short due to declining cellular energy, specifically NAD+. Learn how low NAD+ affects healing and collagen, and why traditional products may not suffice. The hosts dive into various NAD+ precursors, testing methods, and how to optimize skin health through diet, fasting, and exercise. They introduce innovative NAD+ formulations that promise visible improvements and discuss common pitfalls in NAD+ strategies. Plus, get practical tips for a skincare routine that boosts your skin from the inside out!

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INSIGHT

NAD Delivery Faces Bioavailability Limits

Exogenous NAD degrades quickly and has low bioavailability whether oral, topical, or IV.
IVs flood the bloodstream but must be titrated and still deliver little to skin specifically.

ADVICE

Use Precursors And Targeted Delivery

Prefer NAD+ precursors (NMN or NR) and improved delivery like liposomal or micronized forms for better absorption.
Use topical delivery to specifically raise NAD+ in skin rather than relying solely on systemic methods.

INSIGHT

Skin Is Low Priority For Systemic NAD+

The body prioritizes essential organs; systemic NAD+ often routes to brain and liver over skin.
To see skin-specific NAD+ benefits, topical application is necessary.

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There’s a point where even the best skincare starts to feel like it’s not doing enough. Serums stack up, results slow down. What no one tells you is that this might not be a product issue, it might be an energy issue. Specifically, cellular energy. NAD+.

You’ll learn why NAD+ declines with age, how that leads to slower healing, collagen breakdown, and pigmentation, and why traditional skincare can’t keep up. We explain the science behind topical NAD+ delivery, how it compares to IVs and supplements, and why your body doesn't prioritize skin when it’s low on resources.

We also break down the best NAD+ precursors (NMN vs NR vs niacinamide), how to track your NAD+ status, and which ingredients actually raise NAD+ levels in skin, not just systemically. You’ll discover how to combine fasting, HIIT, and smart supplementation to build an energy-optimized skincare routine that works from the inside out.

Plus, we reveal the research behind NAD+ Apex™, the latest innovation from Young Goose that boosts epigenetic repair and reduces wrinkle depth by 15% in just 10 weeks.

If you want your skin to keep up with your biohacking lifestyle, this episode is your protocol for recharging skin at the cellular level.

What's Discussed:

(00:06) When Your Skin Stops Responding—This Might Be Why

(16:07) The Real Way to Raise Your NAD+ (Hint: It’s Not Just Supplements)

(22:01) What Happens When You Flood Your System with NAD+

(37:32) Why Your NAD+ Supplement Isn’t Helping Your Skin

(43:52) The Skincare Ingredient Everyone’s Talking About—But Most Get Wrong

Find more from Young Goose:

The YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body’s anti-aging breakthrough → Body Cream
Spermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for → Spermidine Serums
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
Instagram: @young_goose_skincare