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Treat Alkalosis By Repleting Chloride
- In metabolic alkalosis from diuretics/heart failure, aggressively replete chloride and potassium rather than only giving volume.
- Monitor urine pH (and urine chloride) to confirm you are reversing bicarbonate retention.
SGLT2s Expand Into HFpEF And Renal Protection
- SGLT2 inhibitors reduce heart-failure hospitalizations across HFrEF, HFmrEF and show benefit in HFpEF.
- They also slow renal decline, suggesting a class effect beyond diabetes care.
Think Bronchiectasis With Recurrent Productive Cough
- Suspect bronchiectasis in patients with chronic productive cough, weight loss, or recurrent infections despite antibiotics.
- Obtain imaging and consider specialist-led airway-directed therapies for severe disease.