Your Microbiome, GLP-1 & Next-Generation Probiotics | Dr. Colleen Cutcliffe
The Gabby Reece Show
Perimenopause, Estrogen and the Microbiome
Colleen links menopausal estrogen decline to microbiome shifts and notes future microbiome-based estrogen tools are emerging.
What if your metabolism, cravings, immune system — even your hormones — are being shaped by your gut?
In this episode of The Gabby Reece Show, Gabby sits down with microbiome scientist and Pendulum co-founder Dr. Colleen Cutcliffe to break down the real science behind gut health — beyond the buzzwords.
From premature birth and early antibiotic exposure to GLP-1, estrogen, cravings, and perimenopause, this conversation connects the dots between your microbiome and nearly every major system in your body.
If you’ve ever thought:
“Why am I gaining weight when nothing changed?”
“Why am I suddenly sensitive to foods?”
“Is this just aging… or something else?”
“Are GLP-1 drugs the only option?”
This episode will shift how you think about your body.
In This Episode, We Cover:
Why the microbiome is connected to all 11 organ systems
How early antibiotic use may affect long-term metabolic health
The truth about GLP-1 — and how your body produces it naturally
Why Akkermansia is considered a “keystone strain”
Gut health and perimenopause: what’s really happening
Estrogen, menopause, and emerging microbiome research
Why cravings may not be about willpower
How stress, aging, and travel deplete your gut
Fecal microbiome transplants — what they are and why they matter
How to rebuild a resilient gut (without extremes or shame)
Key Takeaway
The goal isn’t perfection.
It’s resilience.
A strong, diverse microbiome helps your body handle stress, hormonal shifts, aging, and even dietary slip-ups. And unlike your genetics — your gut can change.
Start with food.
Use tools wisely.
Pay attention to your body.
Connect with Dr. Colleen Cutcliffe
Website: https://pendulumlife.com
Instagram: @pendulumlife
Dr. Cutcliffe on Instagram: @drcolleencutcliffe
Connect with Gabby
Website: https://gabbyreece.com
Instagram: @gabbyreece https://www.instagram.com/gabbyreece
YouTube: The Gabby Reece Show https://www.youtube.com/@GabbyReece
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