Your Microbiome, GLP-1 & Next-Generation Probiotics | Dr. Colleen Cutcliffe
The Gabby Reece Show
Cravings, Willpower and Microbial Signals
Gabby and Colleen reframe cravings as microbial signaling, encouraging observation and tactical responses rather than shame.
What if your metabolism, cravings, immune system — even your hormones — are being shaped by your gut?
In this episode of The Gabby Reece Show, Gabby sits down with microbiome scientist and Pendulum co-founder Dr. Colleen Cutcliffe to break down the real science behind gut health — beyond the buzzwords.
From premature birth and early antibiotic exposure to GLP-1, estrogen, cravings, and perimenopause, this conversation connects the dots between your microbiome and nearly every major system in your body.
If you’ve ever thought:
“Why am I gaining weight when nothing changed?”
“Why am I suddenly sensitive to foods?”
“Is this just aging… or something else?”
“Are GLP-1 drugs the only option?”
This episode will shift how you think about your body.
In This Episode, We Cover:
Why the microbiome is connected to all 11 organ systems
How early antibiotic use may affect long-term metabolic health
The truth about GLP-1 — and how your body produces it naturally
Why Akkermansia is considered a “keystone strain”
Gut health and perimenopause: what’s really happening
Estrogen, menopause, and emerging microbiome research
Why cravings may not be about willpower
How stress, aging, and travel deplete your gut
Fecal microbiome transplants — what they are and why they matter
How to rebuild a resilient gut (without extremes or shame)
Key Takeaway
The goal isn’t perfection.
It’s resilience.
A strong, diverse microbiome helps your body handle stress, hormonal shifts, aging, and even dietary slip-ups. And unlike your genetics — your gut can change.
Start with food.
Use tools wisely.
Pay attention to your body.
Connect with Dr. Colleen Cutcliffe
Website: https://pendulumlife.com
Instagram: @pendulumlife
Dr. Cutcliffe on Instagram: @drcolleencutcliffe
Connect with Gabby
Website: https://gabbyreece.com
Instagram: @gabbyreece https://www.instagram.com/gabbyreece
YouTube: The Gabby Reece Show https://www.youtube.com/@GabbyReece
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