Moonshots with Peter Diamandis

Brian Elliott, Co-founder and CEO of Blitzy, leads an AI startup focused on autonomous enterprise software and large-codebase automation. He discusses Blitzy’s $200M raise and practical deployment experiences. The conversation covers Google’s AI-driven earnings, GPT‑5.5 vs Claude Mythos, compute scarcity, Pentagon and White House model oversight, ocean and orbital data centers, and private-equity–led enterprise AI shifts.

Dave Blundin, founder and VC with practical startup scaling chops. Salim Ismail, ExO founder and exponential-org strategist. Alex Wissner-Gross, MIT-trained computer scientist and entrepreneur. Steven Kotler, bestselling author on flow and peak performance. They debate Elon’s Mars compensation, nonprofit-to-for-profit AI shifts, robotics scaling and factories, humanoid vs specialized robots, trial fallout for OpenAI, and visions of AI-driven labs and consumer futures.

A fast tour through the AI arms race, from GPT 5.5 and Kimi K2.6 to the battle over chips, power, and cloud dominance. It also dives into self-hosted models, always-on assistants, deepfake-proof identity, AI reshaping jobs and medicine, and robotics finally moving into daily life.

David Sinclair, Harvard geneticist and longevity researcher, dives into AI finding new molecules in his lab, surprising concerns around GLP-1 drugs, and bold work on reversing blindness and other age-related decline. They also touch on telomeres, muscle and hormone support, stressed plants, indoor health, and the mindset behind aging well.

David Sinclair, Harvard genetics professor and longevity biotech entrepreneur, dives into human age-reversal trials, why the eye is the first proving ground, and the race from gene therapy to a scalable longevity pill. He also gets into lifespan timelines, his current routine, heart-risk tracking, diet changes, and the role of sleep, stress, and social connection.

In this episode, the mates center on the Iran oil shock as a broader system shock, Anthropic’s Claude Design and the “unhobbled” frontier-lab threat to vertical software, the AI job transition, UAP disclosure, the power and geopolitics of data centers, China’s solar and robotics push, and the future of entrepreneurship and agency. Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends   Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360 Salim Ismail is the founder of OpenExO Dave Blundin is the founder & GP of Link Ventures Dr. Alexander Wissner-Gross is a computer scientist and founder of Reified – My companies: Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding      Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy   Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter  _ Connect with Peter: X Instagram Connect with Dave: Web X LinkedIn Instagram TikTok Connect with Salim: X Join Salim's Workshop to build your ExO  Connect with Alex Website LinkedIn X Email Substack  Spotify Threads Listen to MOONSHOTS: Apple YouTube – *Recorded on April 21st, 2026 *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice. Learn more about your ad choices. Visit megaphone.fm/adchoices

AI panic spills into real-world attacks, while young workers face an early hiring squeeze and workers train systems that may replace them. The conversation jumps to AI-run stores, data centers moving off-planet, and Amazon challenging Starlink in the satellite race. Then it gets even wilder with AI-made religions, engineered sports, brain implants, immortality, mind uploads, and life beyond Earth.

AI power struggles take center stage as Elon Musk, Sam Altman, OpenAI, xAI, and Anthropic collide over lawsuits, valuations, and the race for agents. The conversation also dives into looming white-collar automation, humanoid robots in China, AI-designed drugs, Bitcoin’s quantum worries, and why energy, education, and EVs may be heading toward abundance.

A fast tour through SpaceX’s public-market buzz, Starlink’s real value, and the race for AI capital. Then it jumps to Claude’s Mythos release, enterprise AI rivalry, and strange questions about machine emotions. There’s also lunar missions, nuclear spacecraft, orbital data centers, quantum risk to Bitcoin, biotech deals, humanoid robots, and one-person unicorns.

This episode was filmed at the 2026 Abundance360 Summit. Learn more at https://www.abundance360.com/  This interview explores the groundbreaking work of Colossal in synthetic biology, de-extinction, and AI integration. Colossal CEO Ben Lamm explains how the company is revolutionizing biodiversity preservation, tackling plastic pollution, and creating living products with immense potential. Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends   Ben Lamm is Co-founder and CEO of Colossal Biosciences Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360 – My companies: Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding      Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy   Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter  _ Connect with Peter: X Instagram Connect with Ben X Instagram Linkedin Listen to MOONSHOTS: Apple YouTube – *Recorded on March 10th, 2026 *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice. Learn more about your ad choices. Visit megaphone.fm/adchoices