

Python Bytes
Michael Kennedy and Brian Okken
Python Bytes is a weekly podcast hosted by Michael Kennedy and Brian Okken. The show is a short discussion on the headlines and noteworthy news in the Python, developer, and data science space.
Episodes
Mentioned books

31 snips
Mar 23, 2026 • 46min
#474 Astral to join OpenAI
They discuss Starlette 1.0 and its new async lifespan API. The Astral team joining OpenAI and what Ruff, uv, and Ty might bring to Codex comes up. A security audit tool for uv and comparisons with pip-audit are covered. They also talk about Python asyncio fire-and-forget changes and how task GC affects background tasks.

Mar 16, 2026 • 46min
#473 A clean room rewrite?
A heated licensing clash over an AI-assisted clean-room rewrite of a popular encoding library. A look at Refined GitHub and small UI boosts that speed developer workflows. A deep dive into PgDog, a Postgres proxy that handles pooling, load balancing, health checks and sharding. Practical patterns for building and testing agentic systems and cautions about unreviewed AI-generated code.

9 snips
Mar 9, 2026 • 29min
#472 Monorepos
A deep dive into managing a Python monorepo with uv workspaces and practical tips for local package workflows. A tour of cattrs for flexible serialization, validation, and converter support. Discussion on learning to program in the AI age and using AI as a tutor. Highlights of a VS Code extension that boosts FastAPI development and deployment.

Mar 2, 2026 • 39min
#471 The ORM pattern of 2026?
A lively dive into preferring raw SQL with dataclasses for AI-friendly, typed data access and performance gains. A maintenance update on pytest-check and added mypy support. A look at dataclass-wizard for fast, typed parsing across formats. A spotlight on SQLiteo, a macOS SQLite browser, and a chat about agents, trust, and how AI shifts development workflows.

6 snips
Feb 23, 2026 • 25min
#470 A Jolting Episode
Inline-snapshot testing for complex data lets tests store expected structures right in the test code. Jolt provides terminal battery intelligence with power, process tracking, and historical graphs for macOS and Linux. Ruff can format Python code blocks inside Markdown safely. Act lets you run GitHub Actions workflows locally using Docker for faster feedback.

24 snips
Feb 9, 2026 • 34min
#469 Commands, out of the terminal
A macOS app that manages long-running developer commands and automates workflows outside the terminal. A one-liner installer approach for Python CLI tools that avoids requiring Python already be present. Deep dive into replacing 15 years of busy-loop subprocess polling with OS-level waiting for better efficiency. A minimal, Rust-based secure Python interpreter designed for sandboxing AI-generated code.

12 snips
Feb 3, 2026 • 31min
#468 A bolt of Django
Rust-backed Django APIs that aim to outpace FastAPI while keeping Django ORM and Admin. A tool to detect leaked asyncio tasks, threads, and event-loop blocking with pytest integration. Practical guides on migrating from Celery to Django Tasks and running Django with SQLite in production. A tiny server-driven JS library for live updates and notes on UTF-8 becoming Python default.

27 snips
Jan 26, 2026 • 32min
#467 Toads in my AI
They walk through GreyNoise IP checks that reveal who or what is scanning your address space. A new targeted profiler, tprof, gets attention for precise function-level performance work. Toad brings a polished terminal UI for interacting with multiple AI backends. FastAPI’s new guidelines for AI-generated code and practical tips on precompiling bytecode for faster Docker startups are discussed.

17 snips
Jan 19, 2026 • 41min
#466 PSF Lands $1.5 million
Discover how to enhance Django management commands with django-click and django-typer for smoother project integration. The Python Software Foundation has secured a transformative $1.5 million sponsorship from Anthropic, boosting initiatives like PyPI security. Uncover the speed secrets behind uv as it's optimized through modern practices. Explore the innovative PyView framework, which mirrors the interactivity of Phoenix LiveView, and catch some light-hearted banter about coding trends and AI-generated prototypes!

13 snips
Jan 12, 2026 • 36min
#465 Stack Overflow is Cooked
Explore a powerful tool called Port-Killer that simplifies managing and killing local ports for developers. Discover how optimizations have tripled the speed of Python's packaging library. Delve into the troubling decline of Stack Overflow's traffic and its potential long-term effects. Uncover the role of AI in developer companies, and hear about CodSpeed for benchmarking performance in CI environments. Plus, learn tips on password security and the fascinating advancements in agentic coding.


