The Carlat Psychiatry Podcast

The discussion dives into the careful titration of clozapine and lamotrigine, emphasizing the importance of slow dosage increases for patient safety. A spotlight on lamotrigine reveals essential guidelines for rash management, particularly in bipolar depression cases. Recent research on panic disorders introduces findings about the effectiveness of sertraline and propranolol for women suffering from panic attacks, highlighting promising treatment options. This insightful conversation emphasizes both the challenges and advancements in psychiatric medication management.

Dr. Josh Feder shares crucial tips for parents on how to discuss school shootings with their kids. He emphasizes the importance of open communication and validating children's feelings. The conversation highlights strategies for ensuring safety and promoting mental health. Additionally, responsible firearm practices are addressed, underscoring their role in creating a secure environment for children.

This discussion highlights the quick vs. slow titration methods of ziprasidone and quetiapine, stressing the importance of personalized dosing. There's an intriguing analysis of quetiapine's extended-release versus instant-release forms, with a focus on managing fatigue during treatment. The mystery of ghost pills adds depth to the conversation, while a clinical trial on pramipexole for resistant depression unveils its potential benefits and safety. The episode serves as a guide for tailored medication strategies in mental health care.

The FDA has approved cyclobenzaprine for treating fibromyalgia, but it comes with significant psychiatric risks, especially for the elderly. The conversation highlights the dangers of combining opioids, muscle relaxants, and benzodiazepines, which can lead to overdose. There's a focus on the 'Holy Trinity' of medications and the legal ramifications for prescribers. Additionally, potential adverse effects, like mania in bipolar patients, are discussed, stressing the importance of evidence-based interventions before medication.

The FDA just approved Ketarx for surgical pain, but the company has its eyes on depression.CME: Take the CME Post-Test for this EpisodePublished On: 08/15/2025Duration: 18 minutes, 30 secondsChris Aiken, MD and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Meds that require special skill to start: Atomoxetine and prazosin, plus a new FDA warning on stimulants.CME: Take the CME Post-Test for this EpisodePublished On: 08/18/2028Duration: 08 minutes, 28 secondsChris Aiken, MD and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Exploring the intricacies of starting psych medications, the hosts discuss the importance of slow titration for antipsychotics to minimize side effects. They highlight potential drug interactions that can elevate medication levels dangerously. A key focus is on the metabolic enzymes affecting antipsychotics, especially for sensitive groups like Asians and first-time users. Listeners learn about the risks of combining clozapine with fluvoxamine, and a Japanese study reveals significant gene interactions impacting antidepressant efficacy. Tune in for valuable insights!

Discover the essential steps before starting psychiatric medication, focusing on patients' hopes and fears. Learn how to provide realistic hope and set expectations effectively. The importance of trust and communication in medication management is emphasized, alongside discussing risks and choices. Dive into innovative treatments like light therapy for bipolar depression, highlighting safety and stabilization effects. An enlightening conversation that prepares both patients and providers for the journey ahead!

We interview psychoanalyst William Meyer on a therapeutic approach to postpartum depression.CME: Take the CME Post-Test for this EpisodePublished On: 07/28/2025Duration: 14 minutes, 18 secondsChris Aiken, MD and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Postpartum depression can morph into bipolar disorder, raising diagnostic challenges with accuracy as low as 15%. New treatments like zarenolone show promise for quick relief, but navigating this transition requires careful evaluation. The discussion also highlights various therapeutic strategies—both medication and non-pharmacological—that are vital to supporting mothers. Family involvement and psychotherapy are emphasized as key elements in the recovery process, showcasing the importance of a comprehensive approach to maternal mental health.