The ZDoggMD Show

Cepheid's chief medical and technology officer returns to talk PCR testing for COVID, flu, RSV, and future variants & viruses not yet discovered.Watch our other episodes with Dr. David Persing here and learn more about molecular testing at Cepheid here.Video with transcript hereClick here for easier navigation through this show's key topics.0:00 Intro 1:27 What happened to flu (influenza) last year (viral exclusion, innate immune response) 3:20 Nasal vaccines and innate immunity 5:10 How SARS-CoV2 evolves to replicate more efficiently 8:33 Do variants evade PCR testing? Experience with H1N1 flu 12:09 False positives and PCR 14:22 How deep do you need to swab? 15:09 PCR vs. Antigen testing 18:41 Four-In-1 PCR testing: flu component, will flu be back? 20:23 RSV update in kids and adults 23:53 The “FluVid” COVID/Flu A + B/RSV 4-in-1 test 26:21 Future proofing testing for new pandemics 29:33 Will SARS-CoV2 become endemic, and how? 32:25 The role of vaccination, breakthroughs, transmission 34:01 Natural infection and vaccination, how long does it last, boostersVideo archive, audio podcast, music parodies, Supporter Tribe membership, merch, social media, and email: https://lnk.bio/zdoggmdSupport us with a 1-time donation and get a personal email thank you from me: paypal.me/zdoggmdMore about Dr. Z: zdoggmd.com/about-z  Learn more about your ad choices. Visit megaphone.fm/adchoices

We're talking delta's end, kids and COVID, natural vs. vaccine immunity, Moderna and more, LIVE 🔥Here's a Kaiser Health News piece on natural vs. vaccine immunity. Here's an interesting Scientific American piece on why kids are so resistant to COVID's bad effects. And here's a piece on how the risk to kids from COVID compares to other dangers. Video hereVideo archive, audio podcast, music parodies, Supporter Tribe membership, merch, social media, and email: https://lnk.bio/zdoggmdSupport us with a 1-time donation and get a personal email thank you from me: paypal.me/zdoggmdMore about Dr. Z: zdoggmd.com/about-z Learn more about your ad choices. Visit megaphone.fm/adchoices

Promising early results for an oral therapeutic for SARS-CoV2. Here's what we know and what it may mean.Here's the topline data from Merck so far.Video with transcript hereVideo archive, audio podcast, music parodies, Supporter Tribe membership, merch, social media, and email: https://lnk.bio/zdoggmdSupport us with a 1-time donation and get a personal email thank you from me: paypal.me/zdoggmdMore about Dr. Z: zdoggmd.com/about-z Learn more about your ad choices. Visit megaphone.fm/adchoices

Are we really going to fire healthcare workers who won’t vaccinate…during a pandemic? Here’s my Alt-Middle take.Here’s a New York Times article on the subject.Full video with transcript.Video archive, audio podcast, music parodies, Supporter Tribe membership, merch, social media, and email: https://lnk.bio/zdoggmdSupport us with a 1-time donation and get a personal email thank you from me: paypal.me/zdoggmdMore about Dr. Z: zdoggmd.com/about-z Learn more about your ad choices. Visit megaphone.fm/adchoices

We're talking LIVE with Dr. Marty Makary about all things COVID!We covered MANY COVID-related topics, including natural immunity, mandates, vaccine spacing, gain of function viral research, managing coronavirus risk in different age groups, and much more. Check out Marty Makary's other episodes with me here.Video: https://zdoggmd.com/marty-makary-7/Video archive, audio podcast, music parodies, Supporter Tribe membership, merch, social media, and email: https://lnk.bio/zdoggmdSupport us with a 1-time donation and get a personal email thank you from me: paypal.me/zdoggmdMore about Dr. Z: zdoggmd.com/about-z Learn more about your ad choices. Visit megaphone.fm/adchoices

Our COVID science should be much better than it is. Here's a breakdown on spacing doses, natural immunity, gain of function research, therapeutics, healthcare worker burnout & much more.Dr. Marty Makary is a Johns Hopkins physician and editor-in-chief of MedPage Today. Here are all our past shows!Full transcript, video and more: https://zdoggmd.com/marty-makary-6/ Topics & Timecodes:0:00 Intro2:35 NIH spending & COVID research7:53 Herd Immunity, was Marty wrong, clickbait headlines11:02 Menstrual changes and vaccines13:08 Boosters and booster mandates16:45 Rabies Diffr’ent Strokes rant18:54 VAERS surveillance21:44 Tinnitus23:32 Spacing second vaccine dose, Johnson & Johnson booster29:34 Natural immunity and a failure of messaging32:40 Silencing debate and heterodox voices36:49 Bullying and shaming in healthcare and nursing shortages44:29 Treatments for COVID at home49:15 Understanding risk51:43 NIH gain of function virus research54:26 Moderna, BARDA, and profit motives in vaccines57:36 Marty’s thoughts on cloth masks and kids1:06:04 Nikki Minaj & Marty1:11:36 9-11 commission for COVIDVideo archive, audio podcast, music parodies, Supporter Tribe membership, merch, social media, and email: https://lnk.bio/zdoggmdSupport us with a 1-time donation and get a personal email thank you from me: paypal.me/zdoggmdMore about Dr. Z: zdoggmd.com/about-z Learn more about your ad choices. Visit megaphone.fm/adchoices

The FDA advisory committee voted this week to reject approval of COVID Pfizer vaccine boosters for healthy people 16 and up. Here's what's up with that, and how we can better understand the booster question for the healthy and those at higher risk. Here's an interview I did with Dr. Vinay Prasad that touched on this. And here's another discussion that features boosters with Dr. Monica Gandhi.Video & Transcript HereVideo archive, audio podcast, music parodies, Supporter Tribe membership, merch, social media, and email: https://lnk.bio/zdoggmdSupport us with a 1-time donation and get a personal email thank you from me: paypal.me/zdoggmdMore about Dr. Z: zdoggmd.com/about-z Learn more about your ad choices. Visit megaphone.fm/adchoices

Tha’ Notorious VP returns to talk about the numbers around mandates, booster science or lack thereof, masking young kids, and more!Check out Dr. Vinay Prasad’s YouTube channel here and here are the other episodes we’ve done together.Transcript, video and more: https://zdoggmd.com/vinay-mandates/ Topics & Timecodes:0:00 Intro 0:31 The science on masking young children 6:29 Criticizing irrational views held by rational people, kids’ masking 9:47 Bangladesh mask study promoting surgical masks over cloth in adults 13:29 Vaccine mandates, do they make sense to actually improve outcomes, an analysis 23:18 What’s going on with irrational college campus COVID policies, the testing industry’s influence on policy 27:16 FDA resignations and the controversy over COVID boosters 29:18 Flaws/bias in Israeli vaccine data sets 32:00 Boosters in healthy people, the FDA resignations, and political pressure 35:42 Creating psychological reactance and tribalization in response to mandates and poor communication 38:05 The John Mandrola myocarditis study controversy 44:04 #medtwitter madness and using vaccines off-label for kids 52:06 The Ivermectin overreaction in the media 54:32 The modern sense-making crisis and the influence of social media in sowing division and culture wars 58:17 Vinay’s possible dystopian scenario on government overreach 1:03:41 Why the haters, and why block people on Twitter, credentialism, Alt-Middle, religion and science, and more Learn more about your ad choices. Visit megaphone.fm/adchoices

Sometimes I think our leaders don't understand human beings. At all.See also a relevant discussion with Dr. Monica Gandhi here.Full video with transcript here.Video archive, audio podcast, music parodies, Supporter Tribe membership, merch, social media, and email: https://lnk.bio/zdoggmdSupport us with a 1-time donation and get a personal email thank you from me: paypal.me/zdoggmdMore about Dr. Z: zdoggmd.com/about-z Learn more about your ad choices. Visit megaphone.fm/adchoices

Immunity (natural and/or vaccine-induced) is the only way past COVID-19. Dr. Gandhi returns to discuss how we get there.Watch all our prior discussions with Dr. Monica Gandhi here.We talk about the bungled messaging around vaccines, masks, and natural immunity, why vaccines decrease actual viral transmission, why the US got hit so hard with Delta & why shame backfires in public health, why masks and lockdowns can't end a pandemic, natural immunity & why a single dose of vaccine should be our recommendation, the correct thinking on "booster" vaccines, the distinction between antibodies levels & B and T memory cells in durable immune responses to coronavirus, why Dr. Gandhi's stance of vaccine mandates and immunity passports has evolved, the high rate of vaccine uptake among doctors, why death is not always the enemy (RIP Frodo), schools and equity (public vs. private), therapeutics like ivermectin, monoclonals, fluvoxamine, and more, turning the pandemic endemic like cold & flu, what's up with Mu variant, and more!Watch the video here.Video archive, audio podcast, music parodies, Supporter Tribe membership, merch, social media, and email: https://lnk.bio/zdoggmdSupport us with a 1-time donation and get a personal email thank you from me: paypal.me/zdoggmdMore about Dr. Z: zdoggmd.com/about-z Learn more about your ad choices. Visit megaphone.fm/adchoices