POD OF JAKE

Joey is Co-Chief Investment Officer at Pantera Capital. Prior to Pantera, he co-founded Augur, a decentralized prediction market platform and solution to the oracle problem. Joey also co-founded Eco, an app which offers a simple balance to let users spend, send, save and make money at the same time. He co-founded a crypto-focused AngelList syndicate which became one of the top fifteen by backing and was an early investor in projects like 0x and Numerai. In 2013, Joey built a point of sale system enabling Bitcoin payments with sound and Bluetooth. He is both a Thiel Fellow and an Edmund Hillary Fellow. Follow Joey on Twitter @joeykrug. [0:59] - How Joey's interest in computers led him to crypto and venture capital [7:25] - The best decisions Joey has made in his early career [12:42] - Joey’s first experiences as an investor and entrepreneur [16:47] - How Joey’s days of betting on horses made him a better investor [21:20] - Joey's experience with the Thiel Fellowship [26:55] - The origin story behind Augur [30:06] - An overview of prediction markets [35:39] - Joey's perspective on Bitcoin maximalism as an early crypto adopter [39:41] - Predicting the dominant blockchain protocol in a multi-chain future [46:13] - Eco's attempt to rethink modern banking and credit card companies [49:15] - Joey's experience working with Dan Morehead at Pantera Capital --- homeofjake.com

Qiao is a Partner at The Defi Alliance. He previously co-founded and served as the Head of Product at Messari, now the leading cryptoasset information platform. He spent his early career working in finance as a quant trader at Tower Research. Alongside crypto, Qiao has become increasingly focused on longevity and the idea that we may be able to cure aging. Follow him on Twitter @QwQiao. [0:59] - How Qiao's background in quant trading led him to crypto [7:49] - Qiao's approach to investing in crypto [15:14] - The asymmetric nature of both crypto and longevity [28:09] - Personal health and longevity [36:47] - Managing stress and anxiety [46:09] - The current state of crypto and predictions for the future --- homeofjake.com

Vijay is the author of the long-form article turned book, "The Bullish Case for Bitcoin". His original piece is one of the most widely read texts ever written about Bitcoin, following Satoshi Nakamoto's White Paper. Vijay's article has been translated into over 20 different languages and read about one million times. In addition to his writing, Vijay was an early employee at Google and a former campaigner for Ron Paul during the 2008 US presidential election. Follow Vijay on Twitter @real_vijay. [0:59] - How Vijay’s experiences at Google and around politics shaped his perception of Bitcoin [12:05] - His approach to writing "The Bullish Case for Bitcoin" [16:00] - Debating the inevitability of Bitcoin [23:42] - The largest risks remaining for Bitcoin [27:08] - Frameworks for considering Bitcoin's possible futures [34:33] - The definition and evolution of money [46:48] - Bitcoin and the characteristics of good money --- homeofjake.com

Dylan is an impact entrepreneur with a track record of building socially conscious technology companies in areas such as civil justice, local democracy, and now mental healthcare. He currently serves as the Founder and CEO of Mindbloom, a mental health and wellbeing brand helping people achieve personal and clinical breakthroughs with at-home, clinician-prescribed psychedelic therapies, beginning with ketamine. Dylan previously served as Co-founder and Chief Growth Officer at Mighty ($100M+ raised) and Co-founder and Head of Marketing at Voter's Friend (acquired by Democracy.com). Learn more about Mindbloom at mindbloom.com. [0:59] - How Dylan's personal story directed him towards positive technology companies [7:12] - Examining the effects of different psychedelics on the human brain [13:50] - Transitioning from recreational psychedelic usage to psychedelic research [18:16] - Preparation, navigation, and integration for psychedelic experiences [28:32] - Dealing with the reservations of mental and emotional change [33:56] - Overcoming the access barrier for psychedelics [39:16] - Leveraging the shift to telemedicine services to grow Mindbloom [45:10] - Towards mainstream psychedelic usage with clinical trials --- homeofjake.com

Raoul is the CEO and Co-Founder of Real Vision and Global Macro Investor. He was previously co-manager of the GLG global macro hedge fund in London and co-head of hedge fund sales in equities and equity derivatives at Goldman Sachs in Europe. Raoul was one of a relatively small number of investors to predict the mortgage crisis of 2008–2009. Today, he spends much of his time focused on crypto and what he calls The Exponential Age. Check out Real Vision's crypto page at realvision.com/crypto and follow Raoul on Twitter @RaoulGMI. [0:58] - Raoul's story and background in macro investing [11:04] - How Raoul first discovered Bitcoin and why he was quickly interested [14:43] - Trading Bitcoin and crypto on macro time frames [22:50] - The Metaverse and The Exponential Age [29:55] - The unprecedented pace of crypto adoption and the limits of Bitcoin maximalism [38:11] - Raoul's belief in social tokens for business model overhaul [45:42] - How crypto can absorb the entire legacy financial system --- homeofjake.com

Julia is an intellectual leader in the rationalist community and the author of the book, The Scout Mindset. She previously co-founded the Center for Applied Rationality, a nonprofit organization devoted to helping people improve their reasoning and decision-making. Julia has hosted the Rationally Speaking Podcast since 2010. Visit her website at juliagalef.com and follow Julia on Twitter @juliagalef. [0:59] - How Julia came to study rationality and decision making [5:04] - Breaking down rationality and decision making [11:09] - Epistemic vs. instrumental rationality [15:39] - The decade-long history of the Rationally Speaking Podcast [21:42] - Soldier Mindset vs. Scout Mindset [29:46] - Seeking truth over comfort [39:53] - Vitalik Buterin's intellectual honesty [47:30] - Recognizing biases and changing your mind [54:17] - Keeping a small identity --- homeofjake.com

George is a digital marketing specialist and the founder of Multiply Marketing where he helps scale great products and ideas across the internet. He is known on Twitter for his thoughts on mental models, first principles thinking, and his creation of @NavalBot, a Twitter bot that resurfaces some of the greatest tweets from Naval Ravikant. Subscribe to George's newsletter, Clouds & Dirt, and follow him on Twitter @george__mack. [0:59] - George's exploration of psychology and technology [5:19] - Internet vs in-person friends [8:59] - The changing dynamics around where to live [20:44] -  Considerations of digital nomads [25:24] - The need for new words to describe our changing world [33:38] - First principles thinking and George's intellectual role models [35:50] - Buffett Coins: a though experiment [44:45] - Contrasting psychological and technological innovation --- homeofjake.com

Steven is cofounder and CEO of Cameo, the world’s leading marketplace for personalized video shoutouts. The company recently raised a $100 million Series C at a valuation north of $1 billion. Steven graduated from Duke University and worked in finance and entertainment prior to launching the company in 2016. [0:59] - What Steven learned from his early entrepreneurial ventures [5:01] - Mindset shifts between the finance and tech industries [6:49] - The importance of not wasting time early in your career [10:29] - Cameo's origin story and its direct-to-fan business model [15:48] - Challenges of scaling an early stage business [18:27] - Evaluating talent and building a strong team [22:44] - Expanding Cameo's offerings [26:19] - Steven's thoughts on Bitcoin and BitClout [31:24] - Geographic influence on new businesses --- homeofjake.com

Vijay is a general partner at Andreessen Horowitz, where he focuses on investments in biopharma and healthcare. As the founding investor of a16z’s Bio Fund, he leads the firm’s investments at the cross section of biology and computer science. Previously, Vijay was the Henry Dreyfus Professor of Chemistry and Professor of Structural Biology and of Computer Science at Stanford University. During his time at Stanford, Vijay co-founded Globavir Biosciences and the Folding@Home Distributed Computing Project for disease research. Vijay remains an Adjunct Professor of Bioengineering at Stanford University and holds a BA in Physics from Princeton University and a PhD in Physics from MIT. Disclaimer: a16z investments are discussed in this conversation. None of the content should be taken as investment advice. See a16z.com/disclosures for more information. [0:59] - How Vijay ended up at the intersection of biology and technology [6:15] - The academic shift from physics towards biology [12:32] - The difficulty of scaling education [16:38] - Vijay's predictions for the future of work and The San Francisco Bay Area [26:31] - Using distributed computing to simulate protein folding with Fold@Home [38:19] - The rising cost of healthcare and where the industry is moving [49:46] - Targeting longevity as a solution to harmful diseases --- homeofjake.com

Vedika is the Chief of Staff at Weekend Fund where she invests in early-stage startups and helps founders with product, community building, and go-to-market strategy. She previously held positions at Mithril Capital and Stripe and helped to scale TrueLayer into a global organization. Vedika was born and raised in India, attended UC Berkeley, and currently live in London. Check out Vedika's website at vedikaja.in and follow her on Twitter @vedikaja_in. [0:59] - Vedika's childhood in India and journey to working in tech [11:21] - The culture shock of moving to America for college [13:51] - How Vedika broke into venture capital and why she knows it's where she's meant to be [21:24] - The correlation between energy and value-add activities [28:38] - Running experiments with Weekend Fund [34:00] - How Vedika's gap year shaped her future [40:55] - Vedika's experience scaling TrueLayer [43:38] - The relationship between hard work and luck --- homeofjake.com