Cardiac Consult: A Cleveland Clinic Podcast for Healthcare Professionals

Steven Nissen, MD, and Luke Laffin, MD, discuss a groundbreaking phase 1 trial of a CRISPR-Cas9 gene-editing therapy targeting ANGPTL3. They explore its potential as a one-time treatment to significantly lower LDL cholesterol and triglycerides, with promising safety and efficacy data that could reshape lipid management.Learn more about C5 Research at Cleveland Clinic.https://my.clevelandclinic.org/research/c5researchLooking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

A. Marc Gillinov, MD, and Tarek Malas, MD, discuss the long-term benefits of mitral valve repair for patients with degenerative mitral valve disease. They explore surgical decision-making, robotic techniques and post-operative recovery strategies like cardiac rehab that support lifelong valve function and optimal patient outcomes. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Kenneth McCurry, MD, and Marie M. Budev, DO, discuss Cleveland Clinic’s leadership in lung and multi-organ transplantation, highlighting innovations like ex vivo lung perfusion (EVLP) and the collaborative care model that supports complex transplant cases. They also acknowledge Lung Transplant Awareness Day, a national initiative aimed at increasing education about end-stage lung disease.Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Tamanna Singh, MD, and Amanda Vest, MBBS, discuss the relationship between obesity and heart failure. They discuss multidisciplinary strategies, including lifestyle interventions and pharmacologic therapies like GLP-1 receptor agonists for managing patients across the spectrum of heart failure. Learn emerging clinical research regarding obesity and heart failure from Cleveland Clinic experts. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Donna Kimmaliardjuk, MD, and Faisal Bakaeen, MD, explore the latest in multi-arterial coronary artery bypass grafting (CABG). They discuss patient selection, surgical techniques and long-term outcomes supported by optimal medical therapy. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

When a heart is weak after a heart attack, cardiac arrest or surgery, mechanical circulatory support (MCS) can help the heart function while it heals or assist patients long-term.  Cleveland Clinic experts discuss MCS devices, specifically the Impella percutaneous left ventricular assist device (LVAD) and extracorporeal membrane oxygenation (ECMO). Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.Meet the presenters:Amar Krishnaswamy, MD - Section Head of Invasive & Interventional Cardiology https://providers.clevelandclinic.org/provider/amar-krishnaswamy/4268366

Amanda Vest, MBBS, explores sex-based differences in heart failure, focusing on biological and social factors that influence disease development, treatment response and outcomes in women. She highlights disparities in risk factors, access to care and clinical trial representation that can influence heart failure outcomes. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Scott Cameron, MD, highlights the underdiagnosis and undertreatment of peripheral artery disease (PAD) in women. He discusses diagnostic challenges and emphasizes the  need for improved screening, female-specific guidelines and more inclusive research to address disparities in care.Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Women are more likely than men to experience atrial fibrillation symptoms. Mohamed Kanj, MD, discusses gender-based differences in atrial fibrillation treatment, including rate control, rhythm control and anticoagulation. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Ravi Ambani, MD, and Aravinda Nanjundappa, MBBS, MD, discuss Cleveland Clinic’s leadership and progress in treating carotid artery disease. Learn how multidisciplinary teams are transforming care with new research on medical and surgical therapies. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.