Cardiac Consult: A Cleveland Clinic Podcast for Healthcare Professionals

Luke Laffin, MD, and Steven Nissen, MD, discuss findings from SURPASS-CVOT, including a secondary analysis evaluating broader cardiovascular and renal outcomes with dual GLP-1 and GIP agonist therapy compared with a first-generation GLP-1 agent. The conversation examines outcomes of the therapy on all-cause mortality and the clinical implications for treating patients with diabetes and high cardiovascular risk.View current clinical trials. https://my.clevelandclinic.org/departments/heart/clinical-trialsLooking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Steven Nissen, MD, and Luke Laffin, MD, discuss late-breaking data from the Phase II KARDINAL Trial evaluating Tonlamarsen, a once-monthly therapeutic for uncontrolled multidrug therapy. They review study design, blood pressure outcomes and the potential clinical role of long-acting injectable therapies to address adherence gaps in real-world hypertension management.View current clinical trials. https://my.clevelandclinic.org/departments/heart/clinical-trialsLooking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Sean Lyden, MD, and Jon Quatromoni, MD, discuss the evolving landscape of vascular clinical trials, highlighting investigational therapies and device-driven innovations. Learn how these trials are shaping evidence-based decision-making, expanding minimally invasive options and influencing future standards of care for aortic, carotid, peripheral arterial and venous disease. View current clinical trials. https://my.clevelandclinic.org/departments/heart/clinical-trialsLooking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Lars Svensson, MD, PhD, and Milind Desai, MD, MBA, discuss contemporary evaluation and management of aortic valve regurgitation, emphasizing advanced imaging and optimal timing of intervention. They examine valve repair versus replacement, durability outcomes and lifetime management considerations at a high-volume valve center.Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Women’s cardiologist Tamanna Singh, MD, and sports medicine physician Marie Schaefer, MD, introduce the WISER (Women's Integrated Sports, Exercise and Research), a multidisciplinary program addressing the cardiovascular, musculoskeletal, and psychosocial needs of women athletes across the lifespan. They outline how its cross‑institute model integrates cardiology, orthopedics, nutrition, psychology, and sports social work to deliver coordinated, evidence‑driven care.Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Eric Roselli, MD, and Patrick Vargo, MD, discuss the contemporary management of aortic coarctation in adults, including late complications, reintervention strategies, and evolving endovascular and hybrid approaches informed by decades of institutional experience. View the research: Late Complications of Aortic Coarctation Repair Can Be Safely Treated   https://consultqd.clevelandclinic.org/late-complications-of-aortic-coarctation-repairLooking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Karlee (Carly) Hoffman, DO, heart transplant cardiologist who manages transplant recipients and heart failure in pregnancy. She discusses multidisciplinary cardio‑obstetrics care. Short preconception counseling, medication tradeoffs, and contraception choices are covered. Postpartum monitoring, mechanical support options, and reproductive planning including genetic testing and alternatives are also highlighted.

The new Haslam-Bailey Family Section of Cardiovascular Genomics and Precision Medicine is integrating genomic data into cardiovascular risk assessment, diagnosis and treatment. Samir Kapadia, MD, and Krishna Aragam, MD, discuss practical applications of genetic testing and emerging gene‑targeted therapies to enable more proactive and precise patient care.Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Oussama Wazni, MD, MBA, and Jeffery Courson, DO, examine the evaluation and management of inherited arrhythmias and genetic cardiomyopathies. They discuss diagnostic strategies like genetic testing and advanced imaging, and the role of multidisciplinary care in precision medicine. The conversation also highlights evolving therapies, including individualized pharmacologic approaches and emerging gene-based treatments shaping the future of care.Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Venugopal Menon, MD, and Abdulla Damluji, MD, discuss the emerging subspecialty of cardiovascular aging and the growing need to tailor cardiovascular care for older adults.  They explore how integrating geriatric expertise into cardiovascular practice can improve diagnostic accuracy, individualize therapy and optimize outcomes for this rapidly expanding patient population.Read more about the Cardiovascular Center for Aging.  https://consultqd.clevelandclinic.org/the-case-for-cardiovascular-centers-on-agingLooking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.