Sci Guys

What is depression? If you're a listener there's a solid chance you already know, but there's also a good chance you'll listen anyway...You can WATCH the podcast over on our YouTube channelHelp keep the show running by supporting us on Patreon!If you'd like to see more of us, follow our socials!sciguys.co.ukTikTokTwitterInstagramFacebookIf you spot any points that need correcting, head to sciguys.co.uk/correctionsFollow the Sci Guys@notcorry / @lukecutforthReferences & Further Readinghttps://www.who.int/news-room/fact-sheets/detail/depressionhttps://www.nimh.nih.gov/health/publications/depressionhttps://www.nhs.uk/mental-health/conditions/depression-in-adults/overview/https://www.nimh.nih.gov/health/topics/depressionhttps://www.mind.org.uk/information-support/types-of-mental-health-problems/depression/causes/https://icd.who.int/browse/2024-01/mms/en#1563440232https://cks.nice.org.uk/topics/depression/diagnosis/assessment/https://www.sciencenews.org/article/chemical-imbalance-explain-depressionhttps://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/mentalhealth/articles/costoflivinganddepressioninadultsgreatbritain/29septemberto23october2022https://www.cdc.gov/aging/depression/index.htmlhttps://www.nimh.nih.gov/health/publications/depression-in-womenhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646325/

Feeling worried? This week we're diving into the topic of Generalised Anxiety Disorder...You can WATCH the podcast over on our YouTube channelHelp keep the show running by supporting us on Patreon!If you'd like to see more of us, follow our socials!sciguys.co.ukTikTokTwitterInstagramFacebookIf you spot any points that need correcting, head to sciguys.co.uk/correctionsFollow the Sci Guys@notcorry / @lukecutforthReferences & Further Readinghttps://www.nhs.uk/mental-health/conditions/generalised-anxiety-disorder/overview/https://www.nimh.nih.gov/health/publications/generalized-anxiety-disorder-gadhttps://www.mind.org.uk/information-support/types-of-mental-health-problems/anxiety-and-panic-attacks/anxiety-disorders/https://www.ncbi.nlm.nih.gov/books/NBK441870/https://cks.nice.org.uk/topics/generalized-anxiety-disorder/diagnosis/diagnosis/https://www.nhs.uk/mental-health/conditions/panic-disorder/

Check out Noah’s music!Massive thanks to Evan for vision mixing and keeping us relatively sane: https://youtube.com/evanYou can WATCH the podcast over on our YouTube channelHelp keep the show running by supporting us on Patreon!If you'd like to see more of us, follow our socials!sciguys.co.ukTikTokTwitterInstagramFacebookIf you spot any points that need correcting, head to sciguys.co.uk/correctionsFollow the Sci Guys@notcorry / @lukecutforthReferences & Further ReadingBackgroundhttps://www.cancer.gov/publications/dictionaries/cancer-terms/def/double-blind-studyhttps://www.rcpch.ac.uk/about-us/our-team/dr-hilary-casshttps://www.theguardian.com/society/2024/apr/18/hilary-cass-report-and-the-trans-rights-debatehttps://www.theguardian.com/society/2024/apr/20/doctor-hilary-cass-warned-of-threats-to-safety-after-vile-abuse-over-nhs-gender-services-reviewhttps://www.youtube.com/watch?v=aeY1BkCxwoIPuberty Blockershttps://tavistockandportman.nhs.uk/news/early-intervention-study-shows-puberty-blockers-are-a-well-received-intervention-in-carefully-selected-patients/https://pubmed.ncbi.nlm.nih.gov/33529227/https://www.plannedparenthood.org/learn/teens/puberty/what-are-puberty-blockershttps://www.scientificamerican.com/article/what-are-puberty-blockers-and-how-do-they-work/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793415/https://www.nytimes.com/2021/05/11/well/family/what-are-puberty-blockers.htmlhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218488https://www.ncbi.nlm.nih.gov/books/NBK547863/https://ncbi.nlm.nih.gov/pmc/articles/PMC9577333/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344188/https://www.ncbi.nlm.nih.gov/books/NBK551662/https://www.nejm.org/doi/full/10.1056/NEJM198112243052602https://wayback.archive-it.org/7993/20170112031859/http:/www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm209842.htmCass Reviewhttps://cass.independent-review.uk/https://cass.independent-review.uk/home/publications/final-report/file:///Users/notcorry/Desktop/CassReview_Final.pdfhttps://www.england.nhs.uk/commissioning/spec-services/npc-crg/gender-dysphoria-clinical-programme/implementing-advice-from-the-cass-review/Criticismshttps://www.youtube.com/watch?v=qGZ1Gfu7XXwhttps://www.thepinknews.com/2022/11/03/tavistock-experts-criticise-acp-uk/https://www.advocate.com/health/hilary-cass-nhs-report-debunkedhttps://stonewall.org.uk/cass-reviewhttps://www.equalityhumanrights.com/statement-final-report-cass-review

The 5th anniversary of Sci Guys means it’s high time we spoke about marijuana. Literally… It’s high time. Check out Noah’s music: https://tr.ee/f9DikNPhdQMassive thanks to Evan for vision mixing and keeping us relatively sane: https://youtube.com/evanYou can WATCH the podcast over on our YouTube channelHelp keep the show running by supporting us on Patreon!If you'd like to see more of us, follow our socials!sciguys.co.ukTikTokTwitterInstagramFacebookIf you spot any points that need correcting, head to sciguys.co.uk/correctionsFollow the Sci Guys@notcorry / @lukecutforthReferences & Further ReadingCannabis Background & BasicsCannabis | WHOhttps://www.who.int/teams/mental-health-and-substance-use/alcohol-drugs-and-addictive-behaviours/drugs-psychoactive/cannabisMarijuana | History, Effects, THC, & Legality | Britannicahttps://www.britannica.com/science/marijuanaHashish | Cannabis, THC, Intoxication | Britannicahttps://www.britannica.com/science/hashishCannabis (Marijuana) DrugFacts | National Institute on Drug Abuse (NIDA)https://nida.nih.gov/publications/drugfacts/cannabis-marijuanaWhat We Know About Marijuanahttps://www.cdc.gov/marijuana/what-we-know.htmlThe Name of Cannabis: A Short Guide for Nonbotanists - PMChttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531363/Hemp | Description, Products, Seeds, Fiber, & Uses | Britannicahttps://www.britannica.com/plant/hempMarijuana and the Brain - How Marijuana Works | HowStuffWorkshttps://science.howstuffworks.com/marijuana3.htmLegality of cannabis - Wikipediahttps://en.wikipedia.org/wiki/Legality_of_cannabisHistory of CannabisHistory of cannabis and the endocannabinoid system - PMChttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605027/On the Preparations of the Indian Hemp, or Gunjah (Cannabis Indica), Their Effects on the Animal System in Health, and Their Utility in the Treatment of Tetanus and Other Convulsive Diseaseshttps://pubmed.ncbi.nlm.nih.gov/30161735/Oldest evidence of marijuana use discovered in 2500-year-old cemetery in peaks of western China | Sciencehttps://www.science.org/content/article/oldest-evidence-marijuana-use-discovered-2500-year-old-cemetery-peaks-western-chinaEffects of Cannabis UseAdverse Health Effects of Marijuana Use - PMChttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827335/Use of Marijuana: Effect on Brain Health: A Scientific Statement From the American Heart Associationhttps://pubmed.ncbi.nlm.nih.gov/35142225/Edible marijuana products and potential risks for pediatric populationshttps://pubmed.ncbi.nlm.nih.gov/35634702/The Scientific History of Cannabinoids | Science| Smithsonian Magazinehttps://www.smithsonianmag.com/science-nature/the-scientific-history-of-cannabinoids-180981561/Health Effects | Marijuana | CDChttps://www.cdc.gov/marijuana/health-effects/index.htmlHow does marijuana affect the brain? Psychological researchers examine impact on different age groups over timehttps://www.apa.org/monitor/2023/06/marijuana-effects-brainCan cannabis kill? Characteristics of deaths following cannabis use in England (1998–2020) - PMChttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716494https://www.cancer.org/cancer/managing-cancer/treatment-types/complementary-and-integrative-medicine/marijuana-and-cancer.htmlhttps://www.dea.gov/drug-information/drug-scheduling

You can WATCH the podcast over on our YouTube channelHelp keep the show running by supporting us on Patreon!If you'd like to see more of us, follow our socials!sciguys.co.ukTikTokTwitterInstagramFacebookIf you spot any points that need correcting, head to sciguys.co.uk/correctionsFollow the Sci Guys@notcorry / @lukecutforthReferences & Further Readinghttps://www.britannica.com/science/fungushttps://www.britannica.com/science/fungushttps://pubmed.ncbi.nlm.nih.gov/22887928/https://www.britannica.com/science/sclerotiumhttps://science.howstuffworks.com/magic-mushroom6.htmhttps://www.dea.gov/sites/default/files/2020-06/Psilocybin-2020_0.pdfhttps://science.howstuffworks.com/magic-mushroom6.htmhttps://www.canada.ca/en/health-canada/services/substance-use/controlled-illegal-drugs/magic-mushrooms.htmlhttps://asm.org/articles/2023/february/psilocybin-and-mental-health-the-magic-in-the-mushhttps://adf.org.au/drug-facts/psilocybin/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277578/https://idp.nature.com/authorize?response_type=cookie&client_id=grover&redirect_uri=https%3A%2F%2Fwww.nature.com%2Farticles%2Fs41598-020-59282-yhttps://www.standard.co.uk/news/health/trial-magic-mushrooms-psilocybin-depression-maudsley-hospital-london-b1120423.htmlhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901083/https://adf.org.au/insights/magic-mushrooms-medicine/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007659/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156539/https://www.theguardian.com/society/2023/dec/14/magic-mushroom-use-grows-in-england-and-wales-ons-figures-showhttps://www.amsterdam.info/drugs/https://en.wikipedia.org/wiki/Legal_status_of_psilocybin_mushrooms

This week we're talking about Molly, and Mandy, or whatever woman's name you want to call MDMA... You can WATCH the podcast over on our YouTube channelHelp keep the show running by supporting us on Patreon!If you'd like to see more of us, follow our socials!sciguys.co.ukTikTokTwitterInstagramFacebookIf you spot any points that need correcting, head to sciguys.co.uk/correctionsFollow the Sci Guys@notcorry / @lukecutforthReferences & Further Readinghttps://www.history.com/topics/crime/history-of-mdmahttps://nida.nih.gov/publications/research-reports/mdma-ecstasy-abuse/what-are-mdmas-effects-on-brainhttps://nida.nih.gov/publications/research-reports/mdma-ecstasy-abuse/what-are-mdmas-effects-on-brainhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878040/https://www.youtube.com/watch?v=jEAr7ThsYewhttps://www.ncbi.nlm.nih.gov/books/NBK538482/https://www.hopkinsmedicine.org/news/newsroom/news-releases/2019/04/psychedelic-drug-mdma-may-reawaken-critical-period-in-brain-to-help-treat-ptsdhttps://pubmed.ncbi.nlm.nih.gov/34708874/https://www.nature.com/articles/s41591-021-01336-3https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820588/https://pubmed.ncbi.nlm.nih.gov/24006318/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639540/https://www.ncbi.nlm.nih.gov/books/NBK482377/

People are using a diabetes drug to lose weight, but does it actually owrk? Are there any risks? Should we even be using drugs for fat loss at all?You can WATCH the podcast over on our YouTube channelHelp keep the show running by supporting us on Patreon!If you'd like to see more of us, follow our socials!sciguys.co.ukTikTokTwitterInstagramFacebookIf you spot any points that need correcting, head to sciguys.co.uk/correctionsFollow the Sci Guys@notcorry / @lukecutforthReferences & Further Readinghttps://www.ncbi.nlm.nih.gov/books/NBK562269/https://healthmedia.blog.gov.uk/2023/09/04/accessing-wegovy-for-weight-loss-everything-you-need-to-know/https://tspace.library.utoronto.ca/bitstream/1807/129409/2/AMED.2023.9946924.pdfhttps://www.ncbi.nlm.nih.gov/books/NBK551568/https://health.ucdavis.edu/blog/cultivating-health/ozempic-for-weight-loss-does-it-work-and-what-do-experts-recommend/2023/07https://www.diabetes.org.uk/about-us/news-and-views/ozempic-and-weight-loss-facts-behind-headlineshttps://www.nytimes.com/2022/11/22/well/ozempic-diabetes-weight-loss.htmlhttps://pubmed.ncbi.nlm.nih.gov/38300808/https://pubmed.ncbi.nlm.nih.gov/38230266/https://www.nice.org.uk/guidance/ta875/chapter/2-Information-about-semaglutidehttps://www.youtube.com/watch?v=laPaezEsteIhttps://www.who.int/health-topics/obesity#tab=tab_3https://www.nhs.uk/conditions/obesity/https://www.niddk.nih.gov/health-information/diabetes/overview/what-is-diabetes/type-2-diabeteshttps://www.nhs.uk/conditions/type-2-diabetes/symptoms/https://www.pewresearch.org/science/2024/02/26/how-americans-view-weight-loss-drugs-and-their-potential-impact-on-obesity-in-the-u-s/https://medlineplus.gov/druginfo/meds/a618008.htmlhttps://www.nhs.uk/conditions/type-1-diabetes/about-type-1-diabetes/what-is-type-1-diabetes/

Use code SCIGUYS at the link below to get an exclusive 60% off an annual Incogni plan: https://incogni.com/SCIGUYSAlexithymia is the inability to understand or recognise emotions, so this week Noah joins us to talk about his feelings... You can WATCH the podcast over on our YouTube channelHelp keep the show running by supporting us on Patreon!If you'd like to see more of us, follow our socials!sciguys.co.ukTikTokTwitterInstagramFacebookIf you spot any points that need correcting, head to sciguys.co.uk/correctionsFollow the Sci Guys@notcorry / @lukecutforthReferences & Further Readinghttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456171/https://www.bbc.co.uk/news/uk-england-suffolk-64253360https://neuro.psychiatryonline.org/doi/10.1176/appi.neuropsych.14070169https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056680/https://www.britannica.com/science/emotion/The-structure-of-emotionshttps://www.sciencefocus.com/the-human-body/what-are-emotionshttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005782/

Use code SCIGUYS at the link below to get an exclusive 60% off an annual Incogni plan: https://incogni.com/SCIGUYS Luke is having a baby - surprise! So this week we're joined by the lovely Rebecca Hanssen to chat about pregnancy & the absolutely insane effects it has on the body... Grab yourself some merch! You can WATCH the podcast over on our YouTube channel Help keep the show running by supporting us on Patreon! If you'd like to see more of us, follow our socials! sciguys.co.uk TikTok Twitter Instagram Facebook If you spot any points that need correcting, head to sciguys.co.uk/corrections Follow the Sci Guys @notcorry / @lukecutforth References & Further Reading https://www.ncbi.nlm.nih.gov/books/NBK559304/#:~:text=Pregnancy%20is%20a%20state%20of,to%20sustain%20the%20growing%20fetus. https://www.britannica.com/science/pregnancy/Anatomic-and-physiologic-changes-in-other-organs-and-tissues https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928162/ https://www.npr.org/sections/health-shots/2023/04/12/1159753316/pregnancy-start-conception https://www.cam.ac.uk/stories/pregnancy-sickness-cause https://www.nhs.uk/pregnancy/related-conditions/common-symptoms/vomiting-and-morning-sickness/ https://www.cdc.gov/ncbddd/folicacid/about.html#:~:text=Why%20folic%20acid%20is%20important,and%20spine%20(spina%20bifida). https://www.nhs.uk/pregnancy/related-conditions/common-symptoms/bleeding-gums/

Delve into the critical safety oversights that led to the Challenger disaster, revealing ignored warnings and the pressures influencing NASA's launch decisions. The hosts humorously connect modern media's evolution and public interest in space travel. Uncover the tragic implications of design flaws, particularly the O-rings, and the psychological impacts on those involved. Reflect on the ethical dilemmas between corporate interests and safety, all while dissecting the legacy of the tragedy with a mix of humor and critical analysis.