Fortune 500: Titans and Disruptors of Industry

Vinod Khosla, venture capitalist and founder of Khosla Ventures, known for early bets on transformative tech. He paints a 2040 where AI handles most labor. He discusses near-free expertise and services, shifts in work and purpose, policy ideas to share AI wealth, and the geopolitical race to win AI's future.

Demis Hassabis, founder and CEO of DeepMind and Isomorphic, is an AI pioneer behind AlphaGo and AlphaFold. He discusses using AI to cure cancer and speed drug discovery. He explains merging teams to build Gemini and how AI could power universal agents, smart glasses, robotics, and a future of radical abundance.

Albert Bourla, Pfizer chairman and CEO who led the company through COVID vaccine triumphs, discusses refocusing Pfizer on science and R&D. He talks about scaling vaccine manufacturing, tackling oncology and AI-driven drug discovery. He also covers pricing/access approaches, rebuilding trust after the pandemic, and bold plans to transform cancer and neuroscience research.

It’s been one year since Vice President Kamala Harris and then-Democratic nominee was coming down to her final days of the 2024 presidential campaign against Donald Trump. She spent 107 days on the road in a bid to earn their vote, but it wasn’t enough. Almost one year later, she’s had time to reflect. In a wide-ranging conversation at Fortune’s Most Powerful Women summit, Harris joined Fortune’s Editor in Chief Alyson Shontell at the Washington National Cathedral to discuss the growing divides between Republicans and Democrats, how the government is not meeting Americans’ basic needs, and why not inviting Elon Musk to the White House was a “mistake”. Learn more about your ad choices. Visit megaphone.fm/adchoices

In a compelling discussion, Jamie Dimon, the longtime CEO of JPMorgan Chase, explores crucial topics like the potential of AI in business and the impact of government policy on the economy. He shares insights on the risks of inflation and recession, along with practical advice for corporate leadership. Dimon expresses skepticism towards Bitcoin but recognizes blockchain's value. He also addresses local politics, touching on the New York mayoral race, and emphasizes the importance of humility and hard work in effective management.

In this engaging conversation, Eric Glyman, CEO and co-founder of fintech powerhouse Ramp, shares insights on building a startup valued at $22.5 billion in just under 2,400 days. He explains how Ramp's novel business model flips traditional corporate card incentives to benefit customers. Glyman discusses the importance of speed in achieving growth and reveals how AI plays a crucial role in automating expenses and enhancing fraud detection. This blend of innovation and urgency fueled Ramp's staggering revenue growth and investor interest.

Julie Sweet, CEO of Accenture and leader in large-scale reinvention, shares her rise from law to leading a 770,000-person company. She discusses AI-driven organizational rewiring. She talks decisive moves in geopolitical crises, building fast decision teams, and why leaders must keep learning as AI reshapes business.