Finding Genius Podcast

When you think of what addiction recovery looks like, you probably don't envision the consumption of psychedelic drugs. On today's episode, Associate Professor of Psychiatry and Behavioral Sciences at Johns Hopkins and author of 47 articles on psychedelic drugs, Matthew Johnson, PhD, explains why and how psychedelic therapy might have a place in addiction recovery after all. His area of expertise lies in understanding the ways in which psychedelic drugs can serve as behavior change agents. This idea is consistent with neuroscience research findings, countless anecdotal stories, and ceremonial use of psychedelic substances in a variety of indigenous cultures. Intrigued by the idea? Tune in to hear all the details and learn more, including: How Dr. Johnson characterizes the commonality between people who benefit from the use of psychedelics (and it's not about religion or spirituality) How psychedelic drug use could help those who suffer from addiction to cocaine, alcohol, or tobacco, as well as cancer-related depression, anorexia, and PTSD When psilocybin pills could become an FDA-approved option for clinical treatment of a variety of disorders Tune in to hear the full discussion.

Dr. Christian Regenbrecht, shareholder, CEO, of CELLphenomics, provides an overview of his company's important work that could assist researchers as they strive to develop new drugs to treat disease. Regenbrecht studied biology and philosophy at the University of Bonn, and continued his postdoc with noted scientist, Hans Lehrach, at the Max Planck Institute for Molecular Genomics in Berlin. Regenbrecht has focused some of his time on improved patient-derived in vitro models, culture technologies, and preclinical efficacy studies. Regenbrecht discusses his extensive work and the innovations that are happening at CELLphenomics. With greater than 400 proprietary patient-derived 3D (PD3D®) cell cultures, CELLphenomics can offer researchers an opportunity to test compounds with a comprehensive screening approach in an, up to, 384 well format. In simplest terms, patient-derived cell cultures are essentially novel multicellular systems newly isolated from primary organs through mechanical and enzymatic dissociation. Within a system such as this, cells that are grown on a proprietary matrix can develop as 3D organoids which are composed of cell clusters preserving the uniquely complex composition of the tissue of origin. Regenbrecht discusses cell types in tumors, specifically focusing on colon tumors. Continuing, he discusses the ways that tumors can metastasize. Regenbrecht explains how they are able to use their processes to isolate exosomes that are secreted into the cell culture. By studying this information, researchers may be able to predict where the next site of metastasization could occur. Regenbrecht explains their mission at CELLphenomics, as a state-of-the-art in vitro service provider positioned to offer high-quality, sensibly priced cell culture models and ultimately assist the biotech and pharma industries to create innovative testings of new anti-cancer drugs. In this podcast: What makes some tumors metastasize? A detailed explanation of exosomes Innovative practices in the biotech industry

Imagine increasing your business' retention rates by 28.9%, and increasing them by over 20% within the first week of making an investment. With a new machine learning application from Bellwethr, you can. CEO and founder, Matt Moody, joins the podcast to discuss the importance of customer retention and how Bellwethr is making it happen. Compelled by the belief that everyone should have access to the power of artificial intelligence (AI) and the motivation to show his customers the range of problems that AI can solve, Matt Moody and his team at Bellwethr are making it easier than ever for businesses and individuals to benefit from this technology. Tune in to learn more, including: How the Bellwethr win-back engine, upsell engine, and retention engine work Why Bellwethr products offer so much more than other business intelligence and data analytics tools What's on the horizon for Bellwethr in the coming year Check out https://www.bellwethr.com/ to learn more.

Tjasa Zajc, podcaster, entrepreneur, head of the "Faces of Digital Health" podcast, a podcast about digital health and healthcare systems technology adoption, talks about the current state of healthcare in developed and developing countries. Zajc talks about her background and the troubling early medical condition that led her to dig deeper into learning about health. After her diagnosis with IBD, Inflammatory Bowel Disease (which in name covers many disorders that can generate chronic inflammation of the digestive tract), Zajc was compelled to learn more, eventually studying healthcare management and economics in order to better understand healthcare beyond the patient perspective. Zajc talks about the modern healthcare experience in various countries and digital technology in healthcare, covering issues such as availability, chronic conditions, and financial expenses. She discusses private insurance versus public healthcare. She provides detailed information on retirement funds and the concept of saving money for health problems that could come later in life, as the issues relate to various cultures and countries. She explains healthcare models, and how people perceive healthcare solutions around the globe. Zajc explains how some countries have a serious lack of qualified medical personnel and thus access to healthcare is a problem in many corners of the globe. Zajc explains how some people have distrust of their own providers or doctors and may travel many miles to see doctors in larger hospital facilities. The business developer entrepreneur and healthcare expert discusses her current work assisting pharmacies with drug management processes and hospital admittance procedures. She discusses how systems can be made more efficient by going digital, which can decrease some potential problems with medical records, drugs, etc. In this podcast: How digital technology could change healthcare for the better, if only… Is private health insurance doing the best job it can to provide coverage for everyone? The tough problem of scant medical access in some countries

Small, medium, large, soft, firm; when it comes to finding a pillow that works for us, these adjectives are pretty much all we have to work with. For this reason, it can be difficult if not impossible to find a pillow that properly supports your head, neck, and shoulders and retains its integrity over time. After years of dealing with this problem, serial entrepreneur Richard Jacobs decided to do something which had never been done before: design the world's first custom-tailored pillow that is both simple and sensical, as well as easy for a person to get. No complicated measurements or calculations are necessary: all that's required is a picture or two of your upper body, which can be sent through The Good Night's Sleep Project app. From there, you can just sit back and wait for your custom-tailored pillow to arrive. With the use of AI computer vision, 14 measurements will be extracted from your photos and serve as a guideline for the creation of a pillow that's completely unique to you. Tune in to learn about all the details and more, including: How and why the wrong pillow could be contributing to your sleep apnea or snoring How the wear on a mattress over time can actually impact the shape of your pillow, and how the custom-tailored pillow accounts for this How the right pillow could be the solution to a variety of sleeping problems Visit https://www.goodnightssleepproject.com/ to learn more and order one for yourself.

Associate Professor at Harvard Medical School, Director of Cell Biology at the Cancer Center at Beth Israel Deaconess Medical Center, and Principal Investigator at Muthuswamy Lab, Senthil K. Muthuswamy, Ph.D. is working to better understand the molecular biology of cancer and the most effective method of treating it by creating organoids from patient tumors. When cultured under the proper conditions, a sample of tissue from a patient's tumor will grow into a 3D structure that resembles the patient's tumor. Once that's been accomplished, the organoid can be used to determine which drugs will most effectively treat the specific tumor at hand. This approach addresses one of the main challenges to chemotherapy and targeted therapy, which is that not all patients will respond to the same drug in the same way—even if they have the same type of cancer. Dr. Muthuswamy's lab is currently working with breast and pancreatic tumors. On today's episode, you will learn: Why two people with a certain type of cancer respond differently to the same treatment What types of research are being done with the use of organoids What the next five years will bring for Dr. Muthuswamy's lab and organoid-based drug and immunotherapy research

David Freedman, a co-founder and the founding CEO of NanoView Biosciences, discusses noninvasive diagnostics and extracellular vesicles. Freedman was essential to NanoView's entry into the expanding extracellular vesicle market with the development and subsequent launch of the ExoView™ R100. He has been a successful entrepreneur for more than ten years, formerly as CTO of eHomes, and President of a computer services company. Freedman is interested in commercialization strategy and organizational build-out, product and services development, tech engineering, as well as automation. Freedman completed his Ph.D. and Postdoc in Electrical Engineering at Boston University. NanoView Biosciences is at the leading edge of exosome discovery and they provide innovative solutions to detect and characterize extracellular vesicles. Freedman explains what extracellular vesicles are, for those who might not be familiar. As he states, extracellular vesicles are like the "Twitter of cells," in that they are tiny messengers, providing a means for cells to transmit biological information from one cell to another. He discusses the history of cell discovery and what current research is finding in terms of exosome discovery. Exosomes, in simplest terms, are membrane-bound extracellular vesicles produced in the endosomal compartment of a typical eukaryotic cell. Freedman explains NanoView Biosciences' platform, which allows researchers to look at the outside and inside of the exosome. NanoView Biosciences' research looks at many different avenues for their tech to provide new answers. Freedman discusses how this important area of bioscience research can potentially provide more information on the mechanisms of cancer cells. He explains how they analyze samples, discussing nanoparticle size and count, as well as biological activity, which can help companies that are developing liquid biopsies and new therapeutics. Continuing, Freedman discusses other noninvasive diagnostics and therapeutic development. In this podcast: What are extracellular vesicles? What important functions do extracellular vesicles perform? The future of therapeutic development

The USC Rocket Propulsion Laboratory was founded in 2005 with the goal of putting an undergraduate student designed and built rocket into space—which is defined as being at least 100 km or about 330,000 feet above Earth's surface. Just this past year, this goal was finally reached. On today's episode, Michael O'Neill and Laura Potterat, media lead and avionics lead at the lab, respectively, share their experiences as members of the team who finally made this happen, the challenges they faced along the way, and what the accomplishment means for their future work. By tuning in, you'll discover: How the work being done at USC Rocket Propulsion Lab could lead to a cheaper and simpler way of obtaining atmospheric data What a peek into the design and function of space rockets looks like The challenge of characterizing the performance of the rocket, including its acceleration and position Check out uscrpl.com to learn more.

Do you ever notice a little bit of blood on your toothbrush while brushing? This isn't uncommon, and most of us just "brush it off" you might say, but the truth is if your gums are bleeding, then you have a wound where bacteria is penetrating the tissue and entering your bloodstream, paving the way for systemic illness throughout your body. James Hyland, DDS, President and CEO of OraVital, discusses oral infections, how to eliminate them, and why traditional brushing and flossing isn't the solution. He also explains the science behind halitosis (also known as bad breath), why it can occur even in the healthiest of mouths, how to address it in your daily oral hygiene routine, and why failing to do so could lead to plaque formation in your brain—the hallmark of Lyme disease, syphilis, and Alzheimer's. On today's episode, you will learn about all of this and more, including: Where bad breath comes from and what it's composed of The most effective way to clean your teeth and gums What Dr. Hyland recommends as the protocol for mouth infection treatment and periodontal disease treatment Learn more by tuning in and visiting www.oravital.com.

Audrey Gaskins, Assistant Professor, Epidemiology at Emory University, delivers an interesting overview of normal sperm motility, causes of abnormal sperm morphology, and the various factors involved with fertility and semen quality. Gaskins' extensive research has focused heavily upon the connections between environmental, dietary, and lifestyle factors with fertility and fecundity in women and men. She has published on the many benefits of folic acid, exceeding levels well above the current recommendations, in regard to preventing anovulation and incident pregnancy loss as well as boosting the success probability of infertility treatment. She is currently working on an NIH grant that is primarily focused on extending her research to study the possible interactions between diet, air pollution, and fertility among groups of women. Gaskins talks about semen quality in men, and some research has shown that male semen quality globally is on the decline, which is of course an area of concern for researchers. She talks about the possible factors that could play a role in the decline in sperm count, discussing lifestyle and environmental exposures, etc. She discusses fertility in detail, and her interests have driven her to study men because men have been understudied in this regard she states. She talks about DNA fragmentation and genetics, in regard to her studies. The professor goes on to discuss how age plays a role and factors into their studies. She talks about semen samples that they study and how they collect information on important variables that could be determinants in studies. And Gaskins discusses seasonal impacts, and other possible pollutants, etc. that could impact semen quality. In this podcast: What environmental factors could impact semen quality? Reasons that semen quality could be decreasing globally Does age play a role in semen quality?