Finding Genius Podcast

Greg Paulsen, the Director of Applications Engineering at Xometry (xometry.com), discusses on-demand manufacturing services, materials, trends, and 3D printing processes. Podcast Points: How is 3D printing changing the way we manufacture products? Current trends in manufacturing Can 3D printing utilize all kinds of materials, or just plastics and metals? As the leader of the Applications Engineering team, Paulsen handles special projects pertaining to material selection, design-for-manufacturing, and technical engineering resources as well. The team at Xometry is heavily involved in pushing technology, communication, and integration, and helping clients to improve their manufacturing supply line. Paulsen provides an overview of Xometry, and how they help to make manufacturing easier. Xometry has been innovating in the space for years, and has assisted the established manufacturing industry through the introduction of AI (artificial intelligence) and machine learning, just to name a few of the areas they excel in. Paulsen talks about 3D printing technologies in detail. From metals to plastics to composites, the world of 3D printing is expanding and has evolved many times since its introduction in the mid 80s. He discusses the goals of Xometry and their approach to additive technologies, and the maturity of the tech innovations. Paulsen explains molds used in traditional manufacturing versus what new technologies such as 3D printing can do to eliminate a lot of set up work and costs. It's an accessible technology that can be distributed to localized manufacturing sources, which improves efficiency. Continuing, Paulsen discusses materials in detail, and the processes and post-processes in parts and products manufacturing. He talks about resin-based printers and the finishes that they can deliver versus how robust they are in terms of structure and engineering. The manufacturing efficiency expert continues his discussion by discussing software options in the 3D printing and manufacturing arena, the evolution of the industry, and what's on the horizon.

The European Space Agency (ESA) ARTES Program is an optional program for members of ESA that supports a number of projects, products, and applications. Instrumentation Engineer, Arnaud Runge, discusses an ESA business application program line called Business Space Solutions. Tune in to learn the following: What type of devices and products have been created by ARTES-supported companies and how they've provided a significant benefit to the wider community In what ways an ARTES-supported laboratory helped to clear an Ebola outbreak in an African village The threat of ice crystals for pilots and air flight, and how predictive satellite data and monitoring can help The Business Space Solutions program line at the ESA is focused on how to go about using all things space-related, such as communications via satellite, positional data, and various technologies to create new products and services for the enhancement of existing services or to meet new needs from different user communities. The types of projects supported by ARTES fall into many categories, including health, telemedicine, insurance, tourism, and precision farming that will help farmers better utilize resources such as water and fertilizer. Runge discusses a few specific examples of the products they've supported, which include a product capable of measuring parameters such as heart rate, blood pressure, and temperature that can be placed in aircrafts and connected to medical doctors on the ground. This would eliminate the need for countless and costly flight diversions. He also talks about a laboratory that specializes in taking biological measurements in the context of epidemics like the recent Ebola outbreak. The technology works by utilizing satellite-based communication methods to connect various specialists with experts on the ground, and by facilitating the development of healthcare and treatment for the patients met. This method of communication would prove invaluable in the event that a natural disaster rendered conventional forms of communication impossible. Learn more about the work being done by visiting https://artes.esa.int/.

Bridge Builders supports companies that work towards accessible mind-training technology through investments. He explains some of these steps from idea to implementation by discussing: How Bridge Builders is a collaborative group rather than a fund and why that makes a difference for investments. Some of the most popular apps they've supported like Headspace to some newer ones with great potential like Insight Timer. Future projects that fit several needs such as mental health support applications. Operating Partner of Bridge Builders, Charlie Hartwell describes the more fluid style of the collaborative investment model. He touches on the 12 companies his group supports and then goes into more detail about some of the applications they've helped bring about, further explaining their steps from idea to implementation. He describes in particular one app that's growing in popularity called Insight Timer. It offers mindfulness inspiration, meditations, and music from over 5,000 teachers around the world. Additional projects include an app that helps with addiction, the Muse headband, and Fabriq, an app that helps organize and enable better intentionality with relationship building, both social and professional. Mr. Hartwell also addresses projects that need more attention and may come under their purview such as research into psychedelic drug potential to treat various struggles such as PTSD. He mentions as well the rise in alternatives to nonwestern medical practitioners—and would like to see the development of that field become more mainstream. For more see https://bbcollaborative.com/. He also posts frequently to LinkedIn and publishes Medium articles.

From shampoo to carpeting to baby bottles, chemicals are prevalent in our everyday items. Author Rick Smith discusses accompanying concerns such as: The depth of this issue, calling it the second great pollution problem facing humanity. Why the health effects of pollution from such chemicals are prevalent and should be taken seriously. Alternatives for many everyday products that are available. Co-author of Slow Death by Rubber Duck: The Secret Danger of Everyday Things and director of Canada's Broadbent Institute, environmentalist Rick Smith describes the research he and co-author Bruce Lourie underwent to see common results of living in close quarters with chemicals. The prevalence of chemicals such as BPA in eating containers raised alarms and he wondered about the health effects of pollution on our bodies from such chemicals. He tells how he and his co-author experimented on themselves over 10 years with their own blood and urine samples. They would establish a baseline first, and then, for example, cook with plastic and retest themselves to see if there was an increase in chemical levels. In most cases, the answer was yes. Mr. Smith details various other household products to be aware of, from shampoo to cosmetics to paint. He explains the danger and prevalence of phthalates and discusses how it can work as a hormonal disruptor in our body. Finally, he offers good news about the results of consumer pressure and tells the listener about safe alternatives for many of these products.

Former IBM Chief Scientist, Dr. Alex Liu, discusses the services provided by RMDS Lab, a community-based ecosystem provider in the artificial intelligence (AI) and big data sector. You will learn: Why AI and data-related projects rarely succeed when handled only by a few data scientists and/or one method or approach How the RMDS platform works and what benefits it provides to data scientists and businesses alike Common misconceptions regarding data sets, data analysis, and the usefulness of data, and how RMDS Lab can help For the past 10 years or so, RMDS Lab has been building a data science and AI community using an ecosystem approach, guided by the belief that little can be accomplished in the field of big data and AI without utilizing multiple approaches, multiple methods, considering many algorithms, and combining the minds of more than just a handful of data scientists. Ultimately, the goal is to make data science-driven projects more adaptable and accessible and thereby increase the benefit they can serve to individuals, communities, organizations, and companies. RMDS Lab invites clients and partners to enter the RMDS platform where they can build profiles and explore projects in the field while counting on an RMDS AI algorithm that will select the right data sets, algorithms, coworkers, and data scientists for a particular project-related goal. In essence, the platform intelligently scans all available tools and resources and selects the ones best suited to a particular problem in the AI and data science field. According to Dr. Liu, this ecosystem-based approach is absolutely necessary when dealing with so many possible approaches, and such massive amounts of data—much of which is dirty or fake. In light of this reality, the RMDS platform also provides tools for cleaning and organizing data. Tune in for the full conversation and check out grmds.org/ to learn more or sign on to the platform.

We all love our pets and want to provide the very best for them. It can be difficult, though, to sort through the varying recommendations on how to provide the very best care for our beloved pets. Grain-free or grain-based diets? Raw food or kibble? Bones or no bones? Dr. Royal, an integrative veterinary medical practitioner in Chicago joins us today to discuss holistic pet nutrition and how we can help prevent and reduce our pets' illnesses through proper nutrition and integrative veterinary care. In this episode, Dr. Royal dispels myths about raw-food pet diets. In doing so, she provides tips on how to safely transition pets to a balanced diet that's free from the preservatives and artificial additives that are commonly found in pet foods worldwide. The key is making sure that your pet's diet is balanced—tune in to find out exactly what Dr. Royal means. For more information, visit https://animaldietformulator.com/.

In this podcast, Gail McIntyre, Ph.D., DABT, Chief Scientific Officer of Aravive, delivers a comprehensive overview of her work as CSO developing options to treat an assortment of diseases. Before arriving at Aravive, Dr. McIntyre was a principal and/or consultant at multiple innovative pharmaceutical and biotechnology-oriented companies. Opening the podcast, Dr. McIntyre discusses in detail all the groundbreaking work they are producing at Aravive, developing treatments to stop the progression of life-threatening diseases. Dr. McIntyre explains how the Aravive system is built upon an approach to target influential signaling pathways that sustain the activation, the migration, and eventual invasion of abnormal cells into otherwise healthy tissue. The scientific officer explains how tumors work to survive in less than ideal environments. She discusses the secretion of interleukins that can affect white cells. She provides a thorough analysis of the varied processes that sometimes work to improve multiple factors for tumor growth that allows them to survive in all kinds of conditions. She talks about their current work studying the effects and impact of select oncology drugs, observing GAS6 levels in monkeys. Dr. McIntyre further explains how select particular doses of drugs can suppress GAS6 levels, specifically in regard to their ongoing study of ovarian cancer. Dr. McIntyre has authored many regulatory submissions and she is a board-certified toxicologist with noted expertise in oncology and infectious diseases, etc.

Dr. Barry Raphael of the Raphael Center for Integrative Education discusses sleep medicine and breathing issues. Dr. Raphael is a skilled practitioner in the field of orthodontics. He is particularly interested in sleep/breathing issues (airway-centered dysfunction) and malocclusion, and the early treatment techniques that can help to avoid them. Dr. Raphael teaches at the Mt. Sinai School of Medicine in New York City, and at the post-graduate level in the US and abroad, and of course at his center, the Raphael Center for Integrative Education in New Jersey. Dr. Raphael is the president of the New Jersey Association of Orthodontists and is a respected authority in his field at large. As Dr. Raphael states, today we know more about sleep and the reasons behind sleep disruption than ever before. He delves into a detailed explanation of how we take air in during our sleep and the processes that take place as we breathe. He explains the kind of suction activity that the chest creates that helps to pull air in through the nose, and when all is functioning properly this is a fairly effortless process and the diaphragm will distribute air evenly throughout the lungs. However, for some, there is 'turbulence,' which is a 'swirling' of the air as it moves through the body that causes a significant amount of negative pressure. Dr. Raphael explains that this can cause the sidewalls of the airway to flutter, which makes noise, and this noise is what we have labeled as—snoring. Snoring, he states, is one of the hallmarks of negative pressure in the airway. Dr. Raphael discusses the discomfort that can be created and the ways to deal with these airway issues. The orthodontics expert outlines other ways that turbulence can be created in the breathing process, specifically detailing nasal issues, and ways that a 'narrowing' can be created that will impact breathing negatively. Continuing, Dr. Raphael discusses the fields of sleep medicine and sleep dentistry and the innovative progress that is being made in them, offering new hope for sufferers. Dr. Raphael says that eight to fifteen percent of the population has sleep apnea, but of those, many never figure out that this is a problem for them at all, leaving the issue unaddressed. He explains the many ways the body tries to adapt during sleep, in order to get the air that it needs. Dr. Raphael explains how apnea can stress the organs, and how it usually is developed over a long history of intermittent breathing issues that occur during sleep. Additionally, he outlines autonomic responses, and how stress affects breathing and the body.

In this podcast, Andres M. Gomez, University of Minnesota, discusses his research in the area of microbiomics. Gomez talks in detail about his field of microbiomics. As he explains, within microbiomics they use many and various techniques to study microbes—how microbiomes function, and how they interact and exist in their environments. His lab focuses on determining factors that play a part in the composition and function/processes of the microbiomes of animals and humans. The lab uses metagenomics, metabolomics, transcriptomics, machine learning and more. Gomez discusses fatty acids and how they are produced as he explains the microbiome and the complex activities taking place there. Microbiome research can deliver valuable information about microbial communities, their environments and critical changes that can take place within the environments. The microbiomics expert talks about information released recently regarding a few case studies of fecal transplantation therapy, which is the transfer of stool into a recipient for treatment purposes. Gomez seeks to fully understand, through extensive research, all of these issues, and the discoveries they make just might provide critical insight into the human microbiome and how it affects our health, and what role it plays in the development of the disease.

Brian Kelly founded BKCM in 2013 after experiencing a well-publicized conversion about the investment potential of Bitcoin and its supporting blockchain technology, an epiphany he chronicled in his book The Bitcoin Big Bang. As CEO, he brings more than two decades of experience managing global macro strategies, as well as building investment funds and independent investment firms from the ground up.