This Week in Virology

In episode 40 of "This Week in Virology", hosts Vincent Racaniello, Dick Despommier, and Alan Dove consider Reston ebolavirus in swine, historical perspective of H1N1 influenza virus emergence and circulation, Tamiflu-resistant H1N1, Tamiflu in Japanese river waters, transmission of H1N1 virus in ferrets, and pneumonia and respiratory failure from H1N1 in Mexico. Links for this episode Reston ebolavirus in Philippine swine Historical perspective on H1N1 virus Salk's 1947 article on flu vaccine failure Persistent legacy of 1918 H1N1 virus Tamiflu resistant H1N1 virus (AP article) Tamiflu in Japanese river waters H1N1 infection of ferrets (article one and two) Pneumonia and respiratory failure from S-OIV in Mexico DNA-based equine WNV vaccine (thanks Peter!) Fundamentals of Molecular Virology by Nicholas Acheson Weekly Science Picks Alan Coming to Life by Christiane Nusslein-VolhardDick Monsters Inside Me from Discovery ChannelVincent Microbeworld

In episode 39 of This Week in Virology, hosts Vincent Racaniello and Dick Despommier discuss virus structure and answer listener questions. Links for this episode Diagrams of virus structures Boston Globe article on Genzyme FDA warning letter to Genzyme (thanks Peter!) Public Health Reports July - December 1918 (thanks Lenn!) Amateur scientists working with professionals (thanks Ennio!) Influenza H1N1 and computer analogies (thanks swiss compass!) Bone marrow transplant to cure AIDS not reported (thanks Andrew!) Paul Offitt interview on vaccines and autism Mark Crislip on vaccines and autism Weekly Science Picks Dick Visual Explanations by Edward R. TufteVincent The Youngest Science by Lewis Thomas

In episode 38 of This Week in Virology, hosts Vincent Racaniello and Glenn Rall chat about koi herpesvirus, H1N1 influenza vaccine produced in insect cells, attack by a rabid raccoon, and measles. Links for this episode: Virus suspected in carp die-off: koi herpesvirus H1N1 influenza vaccine produced in insect cells with baculovirus vectors Outbreak of measles in Wales Production of influenza vaccines in cell cultures: MDCK, Vero, PER.C6, EB66, insect (thanks Peter!) Weekly Science Picks Glenn Riddled with Life by Marlene Zuk Vincent All the Virology on the WWW

In episode 37 of This Week in Virology, hosts Vincent Racaniello, Alan Dove and guest Eric Freed talk about vesivirus contamination of bioreactors, pandemic influenza, maximizing the effect of vaccination by targeting children, chikungunya virus, and open access scientific journals. Links for this episode: Genzyme shuts down manufacturing of two enzyme drugs because of vesivirus contamination Brazilian H1N1 isolate is not novel WHO interactive H1N1 map Targeting children maximizes the effect of vaccination Chikungunya virus and Aedes mosquitoes Viruses, an open-access virology journal iBioSeminars A field study of virus removal in septic tank drainfields Weekly Science Picks Alan Forrest Mims (website) Vincent The Machinery of Life by David S. Goodsell

In episode 36 of This Week in Virology, hosts Vincent Racaniello, Alan Dove, Dick Despommier and guest Hamish Young discuss the 2009 influenza pandemic, first 2009 H1N1 vaccine, hunting mosquitoes with midges, vaccine-associated polio in India, and adenoviruses. Links for this episode: WHO calls it a pandemic Novartis produces test run of H1N1 vaccine Midge keeps invasive mosquito in check Two cases of vaccine-associated polio in India BBC interactive map of influenza cases Outbreak of adenovirus type 14 Weekly Science Picks Dick The World’s Water by Peter H. Gleick Hamish Guns, Germs, and Steel by Jared Diamond; Complications by Atul Gawande Alan Eurekalert Vincent Respectful Insolence

In episode 35 of This Week in Virology, hosts Vincent Racaniello, Alan Dove, Dick Despommier and guest Richard Kessin talk about Lujo virus, a new arenavirus, influenza, WHO rewriting pandemic rules, adjuvants, and a brief history of microbiology. Links for this episode: Lujo virus, a new arenavirus Is CDC too optimistic about influenza? WHO to rewrite pandemic rules Adjuvant at wikipedia Avery, MacLeod, McCarty 50th anniversary ( pdf) Weekly Science Picks Dick Three papers on origins of infectious diseases (one, two, three) Rich An Imperfect Lens by Anne Roiphe Alan Zotero, a FireFox plugin Vincent e! Science News

In episode 34 of This Week in Virology, hosts Vincent Racaniello, Alan Dove, and guest Stephen Morse discuss progressive vaccinia in a smallpox vaccinee, arsenic and influenza in mice, facemasks and flu transmission, and antigenic and genetic analyses of the new H1N1 influenza virus. Links for this episode: Progressive vaccinia in a military smallpox vaccinee Arsenic compromises the immune response to influenza in mice Facemasks prevent flu transmission in a mathematical model Serum cross-reactive antibody response to the new H1N1 influenza virus Antigenic and genetic characteristics of the new H1N1 influenza viruses Preparation of influenza virus vaccine seeds Paul Ewald on the evolution of virulence Weekly Science Picks Alan Org-Mode Vincent Human/Swine A/H1N1 Influenza Origins and Evolution Stephen The Origin of Species by Charles Darwin

Vincent, Alan, Dick, and Raul Andino live at ASM discussed cytomegalovirus infection and blood pressure, restriction of avian influenza viral replication at low temperature, first isolation of West Nile virus in PA, and current status of influenza. Hosts: Vincent Racaniello, Alan Dove, Dick Despommier, and Raul Andino Links for this episode: Cytomegalovirus infection causes an increase of arterial blood pressure Avian influenza virus glycoproteins restrict virus replication at low temperature First West Nile virus isolation of the year in PA CDC press release of 18 May 2009 Glaxo's influenza vaccine with adjuvant NY Times article on Guillain-Barré and a more scientific view Weekly Science Picks Dick - National Museum of the History of Science and Medicine, Leiden Alan - Beginning Mac OS X Programming Vincent - Vaccinated by Paul Offit Raul - HubbleSite

In episode 32 of This Week in Virology, hosts Vincent Racaniello, Alan Dove and guest Raul Rabadan converse about polio survivors in iron lungs, bocavirus, structure of mimivirus, and genome sequence analysis of influenza H1N1 viruses. Links for this episode: Death of Marsha Mason, who lived 60 years in an iron lung First discovery of bocavirus in human stool Structural studies of the giant mimivirus Pandemic potential of H1N1 influenza virus Was swine flu a lab accident? Bloomberg and NY Times articles Hong Kong virologist says new H1N1 strain is ‘unstable’ Article by John Barry on site of origin of 1918 influenza

In episode 31 of This Week in Virology, hosts Vincent Racaniello, Alan Dove, Dick Despommier and guest Marc Pelletier summarize the past week’s influenza H1N1 activity, and discuss parvovirus infection of dogs and humans. Weekly Science Picks Marc Celestia, an application Dick US Geological Survey website Alan Society for Amateur Scientists website Vincent Sneeze, an online game