MDS Podcast

In this episode, Dr. Hugo Morales interviews Dr. Bas Bloem and Dr. Victor Fung, co-authors of "The Wisdom of Our Mentors: Clinical Pearls in Movement Disorders," who share clinical pearls and discuss how mentors' and mentees' interactions are at the center of mentorship in movement disorders and the MDS. Read the article

In this Hot Topic episode, Dr. Michele Matarazzo interviews Dr. Nir Lipsman on the Focused Ultrasound-mediated Blood-Brain Barrier Opening, from technical challenges to current evidence and future perspective of this promising technology that could provide a new way to deliver drugs in the brain.

Prof. Paresh Doshi and Dr. Sara Schaefer discuss the outcomes of unilateral radiofrequency pallidotomy in focal and hemidystonia patients, comparing lesioning techniques like Gamma Knife Radiation Therapy and deep brain stimulation. They explore the effectiveness of pallidotomy in dystonia cases and the transition to deep brain stimulation, highlighting challenges in predicting patient results and the preference for radiofrequency lesioning over MRGFUS technology.

Dr. Michele Matarazzo interviews Dr. Robert Chen about the rapidly expanding applications of focused ultrasound-based neuromodulation in neurology, particularly in movement disorders, from tremor to Parkinson's disease. Tune in to uncover the future and potential of non-invasive neurotherapies that are setting new standards in research and patient care.

Prof. Tiago Outeiro interviews Dr. Jing Zhang on his most recent paper in the Movement Disorder Journal on the erythrocytic alpha synuclein and the gut microbiome. Together they discuss alpha synuclein spreading pathology and the promising future of blood biomarkers for Parkinson’s disease. Journal CME is available until March 02, 2025 Read the article.

Dr. Jussi Sipilä joins Dr. Eduardo de Pablo-Fernandez to discuss the interesting findings of the article on mortality rate in Parkinson's disease using nationwide data from multiple health registries in Finland. Read the article

Dr. Michele Matarazzo interviews Prof. Andrea Kühn on her recently published article showing the potential of local fields potentials to help the programming of deep brain stimulation in patients with Parkinson's disease. Read the article

Dr. Avenali and Prof. Valente discuss deep brain stimulation in GBA-related Parkinson's disease, highlighting its efficacy and risks. They delve into cognitive impacts, outcomes analysis, and the importance of genetic profiling for personalized treatment

Dr. Sara Schaefer discusses with Prof. Xiang Gao and Xinming Xu on their study utilizing the UK biobank to explore the risk of Parkinson's disease as it relates to family history of Alzheimer's disease (AD) or dementia and to the polygenic risk score for AD. They further explore the common pathophysiological underpinnings for protein aggregation in the brain. Read the article

Dr. Pasquini discusses the findings of his collaborative study that has helped to understand the progression of rest postural and kinetic tremor in Parkinson's disease. Read the article