The Human Upgrade: Biohacking for Longevity & Performance
Dave Asprey
For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.This isn’t just self-improvement - it’s human enhancement backed by data.Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.
Episodes
Mentioned books
45 snips
Jan 18, 2024 • 1h 16min
Biohack Like a Woman – Aggie Lal : 1126
Aggie Lal, a bestselling author and health coach known for her work in women's biohacking, shares her insights on how women can optimize their health. She dives into the importance of understanding menstrual cycles, the challenges of nutritional safety, and approaches tailored to women's unique needs. Aggie emphasizes moving away from calorie counting towards nutrient density, and discusses the impact of hormonal cycles on wellness. With personal anecdotes and actionable advice, she empowers women to reclaim their health and navigate the complexities of biohacking.
Jan 16, 2024 • 1h 9min
From Tech to Table: Kimbal Musk's Culinary Revolution : 1125
Kimbal Musk, restaurateur and co-founder of urban farming venture Square Roots, shares his culinary journey from tech to table. He emphasizes the transformative power of food in building community and the importance of regenerative farming practices. During a live cooking session, Kimbal reveals tips for preparing the perfect grass-fed steak, highlighting how the energy in cooking affects flavor. He discusses his new cookbook, which aims to inspire families with accessible recipes, ultimately connecting food, love, and sustainable practices.
42 snips
Jan 11, 2024 • 58min
Gratitude & Grit: How To Grow in 2024 – Gary Vaynerchuk : 1124
Gary Vaynerchuk, a self-made entrepreneur and digital marketing pioneer, shares his journey from a lemonade stand to co-founding VaynerMedia. He emphasizes the importance of gratitude as a remedy for burnout and contrasts pursuing joy over wealth. Gary discusses the evolving social media landscape and the value of kind candor in leadership. He advocates for learning from elders and champions emotional intelligence in business, all while inspiring listeners to follow their passions and embrace the challenges and transformations ahead in 2024.
300 snips
Jan 9, 2024 • 1h 16min
A Healthy Gut Can Reverse Disease – Dr. Steven Gundry : 1123
In this enlightening conversation, Dr. Steven Gundry, a renowned cardiothoracic surgeon and a pioneer in nutrition, delves into the transformative power of gut health. He shares groundbreaking insights from his latest research, including the connection between the microbiome and disease reversal. Topics include the impact of dietary choices, the truth about gluten and leaky gut, and surprising findings on nicotine and longevity. Dr. Gundry emphasizes the importance of understanding our diet's role in hormone regulation and mental health, challenging conventional beliefs with compelling evidence.
71 snips
Jan 5, 2024 • 41min
NAD+: A Quantum Leap in Biohacking – Dr. Gregory Kelly : 1122
Dr. Gregory Kelly, a naturopathic physician and lead product formulator at Neurohacker Collective, shares his expertise on NAD+. He delves into its vital role in longevity, cognition, and energy levels, clarifying the differences between NAD supplements like NR, NMN, and Niacinamide. Dr. Kelly compares the effectiveness of IV treatments with supplements, revealing the cost-benefit analysis of each. He also introduces the innovative Qualia NAD+ formula and discusses how timing and synergy can enhance supplement efficacy, paving the way for better health and performance.
109 snips
Jan 4, 2024 • 1h 26min
How to Relentlessly Prioritize Your Life – Jesse Itzler : 1121
Jesse Itzler, an entrepreneur and triathlete known for co-founding Marquis Jet, shares his secrets to prioritizing life effectively. He discusses the importance of organization, balancing professional and personal commitments, and his unique strategies for managing time and email. Itzler emphasizes embracing flexibility over rigid to-do lists and the transformative power of endurance challenges. The conversation also covers innovative fitness and longevity practices, offering insights into how to stay mentally and physically young while pursuing meaningful experiences.
8 snips
Jan 2, 2024 • 1h 1min
The Expert In Your Face: Youthful Skin Without Surgery – Dr. Anthony Youn : 1120
Dr. Anthony Youn, aka "America’s Holistic Plastic Surgeon," discusses how to achieve youthful skin without surgery. He introduces his concept of Autojuvenation, emphasizing natural alternatives that challenge traditional plastic surgery norms. The podcast dives into the effectiveness of collagen supplements, the importance of non-invasive treatments, and how to choose between natural and medical-grade skincare. Youn also shares common skincare mistakes and holistic solutions for hair loss, providing listeners with insights for a more youthful appearance.
133 snips
Dec 28, 2023 • 59min
Urolithin A: The Miracle Compound - Dr. Dominic Denk : 1119
In this conversation, Dr. Dominic Denk, a physician specializing in aging and cancer research at University Hospital Frankfurt, illuminates the groundbreaking benefits of Urolithin A. Find out how this powerful compound supports mitochondrial health, boosts muscle strength, and enhances cognitive function. Dr. Denk dives into its role in cancer prevention and autoimmunity while discussing the differences in healthcare approaches between the U.S. and Germany. Uncover the potential of Urolithin A to revolutionize your wellness routine and longevity.
31 snips
Dec 26, 2023 • 1h 8min
How & Why You Age, And What It Takes To Be 'Young Forever' – Mark Hyman, M.D. - End of Year Best-Of Episode! : 1118
Mark Hyman, M.D., a functional medicine expert and author of "Young Forever," joins the discussion on the science and secrets of aging. He shares the Top 10 hallmarks of aging and the crucial role of inflammation in aging, introducing terms like "Inflammaging." Discover how dietary choices, metabolic flexibility, and lifestyle changes can reverse biological age—Hyman effectively reduced his own by 20 years! They also explore innovative approaches like hyperbaric chambers and practical strategies to enhance healthspan and longevity.
28 snips
Dec 21, 2023 • 1h 14min
Change Absolutely Everything With One Hack – Robert Waldinger, M.D. - End of Year Best-Of Episode! : 1117
Robert Waldinger, M.D., a Harvard psychiatrist and leader of the Harvard Study of Adult Development, shares insights from an 80-year research project on happiness. He reveals that strong, quality relationships are essential for long-term health and well-being. Listeners learn about the importance of social fitness, how relationships can combat loneliness, and the surprising value of casual connections. Waldinger also discusses attachment styles and offers practical tools to enhance relationships, making a compelling case for nurturing our social ties.
