This Week in Evolution

Nels and Vincent discuss how the loss of an enzyme in marine mammals millions of years ago now makes them at risk for neurotoxicity caused by human-made organophosphorous pesticides. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Ancient lossesof paraoxonase I (Science) Big Yellow Taxi (YouTube) Image credit Letters read on TWiEVO 34 Hey farmer farmer put away the chlor-pyri-fus I don't care about spots on my apples Leave me the manatee and walruses Science Picks Nels - New dinosaur discovered in Utah Vincent -The Song of the Dodo by David Quammen Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent are astounded by the finding of an insect-derived virus in a fungus that manipulates the behavior of flies. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Virus in fungus in fly (bioRxiv) On a leaf, no one can hear you scream (TWiV 443) Nels gives Benzer Lecture (YouTube) Domestication of fungal fly pathogen (bioRxiv) Sequencing E. muscae genome (10X genomics) Eisen's twitter stream on new iflavirus (Twitter) Science Picks Nels - Mindsuckers; getting photos; Anand Varma photos Vincent - Happy Birthday Gregor Mendel Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Matt joins Nels and Vincent to discuss the neutral theory of evolution and its rejection in light of genome-scale data. Hosts: Nels Elde and Vincent Racaniello Guest: Matt Hahn Become a patron of TWiEVO Hahn Lab Molecular Population Genetics by Matt Hahn Neutral theoryin light of natural selection (Mol Biol Evol) Neutral Sequence Fallacy(Assembly of Fragments) Splendor and miseryof adaptation (BMC Biol) Image credit Letters readon TWiEVO 32 Science Picks Nels - Inaugural Transposon Day Vincent - How many human genes? Listener Pick Anne- Plants repeatedly lose ability to obtain nitrogen Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent present ancient hepatitis B virus genome sequences from Bronze Age to Medieval period human remains. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Ancient hepatitis B virus genomes(Nature) Even more ancient HBV genomes(bioRxiv) Image credit Letters readon TWiEVO 31 Science Picks Nels - Sampling whale breathwith drones (Preprint) Vincent - Verge Science Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent reveal how a motor protein in corn causes preferential transmission of chromosomes to egg cells, leading to non-Mendelian inheritance. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Molecular Evolution and the Cellmeeting Selfishcorn chromosomes (Cell) Dawe Lab- neocentromeres and meiotic drive Image credit Letters readon TWiEVO 30 Science Picks Nels - Craypot stinkhorn mushroom (Colus pusilus) Vincent -Doubts raised over plan to release herpesvirus to wipe out carp Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent discuss the evolution of blood feeding to nonbiting in a mosquito, and evolution of bacterial virulence in the house finch caused by incomplete host immunity. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Molecular Evolution and the Cell meeting Mosquito evolution from blood feeding to nonbiting (PNAS) Mosquito blood feeding is not a free lunch (virology blog) Incomplete immunity and evolution of virulence (Science) Image credit Letters read on TWiEVO 29 Science Picks Nels - IDEA and Impossible Foods Vincent - it is NOT junk Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Sarah Tishkoff joins Nels and Vincent to explain work from her laboratory on the genetic basis of skin pigmentation in Africans. Hosts: Nels Elde and Vincent Racaniello Guest: Sarah Tishkoff Become a patron of TWiEVO Molecular Evolution and the Cell meeting Sarah AMA on Reddit Genetics of African skin pigmentation (Science) Image credit Science Picks Nels - In Defense of Plants (Shrew Loo) Vincent - Contribution of NIH funding to new drug approvals Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Taking a cue from the recent frigid weather, Nels and Vincent explore how modifications of a neuronal cold-sensing channel regulate diminished cold sensitivity in hibernating mammals. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Why ground squirrels and hamsters don't mind the cold (Cell Rep) Image credit Letters read on TWiEVO 27 Science Picks Nels - Undergrad podcasters from Stonehill College Vincent - Viruses at Target Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Vinny Lynch joins Nels and Vincent to discuss how a zombie gene in elephants protects these large, long lived animals from cancer. Hosts: Nels Elde and Vincent Racaniello Guest: Vinny Lynch Become a patron of TWiEVO Lynch Lab Elephant zombie LIF gene induces apoptosis (bioRxiv) Image credit Science Picks Nels - Animalism Vincent - Voyager I fires up thrusters after 37 years Vinny - Rollin' Wild Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent discuss a genomic analysis of the passenger pigeon, which shows that species with large and stable populations may be at risk of extinction after a sudden environmental change. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Passenger pigeon genomic diversity (Science) Image credit Letters read on TWiEVO 25 Science Picks Nels - Video of nematophagous fungi Vincent - How should novelty be valued in science? John - Evo-Devo (Despacito Biology Parody) Melanie - What's in John's Freezer Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv