This Week in Evolution

Nels and Vincent continue their discussion of SARS-CoV-2 from an evolutionary viewpoint, including function of the furin cleavage site, whether Vervet cells are an informative system, another bat isolate, and a nomenclature to assist genomic epidemiology. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO SARS-CoV-2 in Vero cells (bioRxiv) More related SARSr virus from bat (bioRxiv) Patient isolates in Vero cells (medRxiv) Nomenclature for genomic epidemiology (bioRxiv) Time stamps by Jolene. Thanks! Science Picks Nels - EvoEco seminars Vincent - Coronavirus book for children Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent continue their discussion of SARS-CoV-2 from an evolutionary viewpoint, focusing on what the genome sequences tell us about the virus. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Clement Chow with COVID-19 (Salt Lake Trib) Scientists exposed to coronavirus (Nature) CoV by Britt Glaunsinger (YouTube) Genetic epidemiology of novel coronavirus (nextstrain.org) Time stamps by Jolene. Thanks! Science Picks Nels - Science Mill Explorer Zone Vincent - COVID-19 treatment and therapy tracker Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent examine SARS-CoV-2 from an evolutionary viewpoint, examining what the spike glycoprotein sequence informs us about the origin of the virus. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Distinct CoV name needed (Lancet) Proximal origin of SARS-COV-2 (virological) CoV spillovers not rare (Goats and Soda) SARS-CoV-2 phylodynamics analysis (virological) Bat CoV surveillance in China (PLoS Path) Image credit Time stamps by Jolene. Thanks! Science Picks Nels - Alejandro Sanchez TED Talk Vincent - WHO SARS-CoV-2 Sitrep Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent dive deep into evolution and consider how new proteins emerged billions of years ago, when there were no other proteins to serve as starting material. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Primordial emergence of a nucleic acid binding protein (bioRxiv) Tawfik laboratory Image credit Letters read on TWiEVO 51 Time stamps by Jolene. Thanks! Science Picks Nels - Universal principled review Vincent - Hostile Planet by National Geographic Listener Pick Courtney - Nightwish Endless Forms Most Beautiful and Shudder Before The Beautiful Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent discuss signatures of sex chromosome evolution revealed by assembly of a young vertebrate Y chromosome from 3-spined stickleback fish. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Assembly of a young vertebrate Y chromosome (bioRxiv) Image credit Letters read on TWiEVO 50 Time stamps by Jolene. Thanks! Science Picks Nels - Genome from a 5,700-Year-Old Wad of Chewed Gum Vincent - NJ Sea-Level Rise Reports Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Rich joins Nels and Vincent for a debriefing on the 4th Ringberg Symposium on Giant Virus Biology in Tegernsee, Germany. Hosts: Nels Elde and Vincent Racaniello Guest: Rich Condit Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Endless giant virus forms most beautiful (TWiV 575) 4th Ringberg Giant Virus Meeting Program (pdf) Photographs by Matthias Fischer Time stamps by Jolene. Thanks! Science Picks Rich - Flightradar24 Nels - Deutsches Museum Munich Vincent - Diversify Microbiology Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent reveal a new choanoflagellate that forms multicellular cup shaped colonies that respond to light to alternate between feeding and swimming behavior. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Microbial accomplices in multicellularity (TWiEVO 11) Light regulated collective contractility (Science) Image credit Letters read on TWiEVO 48 Time stamps by Jolene. Thanks! Science Picks Nels - How to write a great science paper by Cormac McCarthy Vincent - Natural Selection Store Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent trace the origins of Saccharomyces cerevisiae strains used to make beer, and find that ales and lagers are made with yeasts that were derived from those used to make European grape wine and Asian rice wine. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Origins of beer yeasts (PLoS Biol) Chateau Jiahu beer Time stamps by Jolene. Thanks! Science Picks Nels - Population fluctuations in 10 biggest cities Vincent - 1.7 million year old rhino tooth (original Nature paper) Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Nels and Vincent analyze the genomes of canine transmissible tumors to provide insight into the worldwide spread of the disease from its origin in a single dog 4000-8500 years ago, and its diversity, mutation, and evolution. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Evolution and mutation of canine transmissible cancer (Science) Clam cancers (TWiEVO 17) Sixth modality of infectious disease (PLoS Path) Time stamps by Jolene. Thanks! Science Picks Nels - Vasa Museum in Stockholm Vincent - Nobel Museum in Stockholm Listener Pick Irene - @EndlessFormsand #PlantScienceFascinatesMe #plantsday Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

At ASM Microbe in San Francisco, Nels and Vincent meet up with Talia Karasov who reveals that in contrast to agriculture, wild plants are colonized by multiple lineages of pathogenic bacteria. Hosts: Nels Elde and Vincent Racaniello Guest: Talia Karasov Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Talia Karasov in the Bergelson lab Arabidopsis thaliana and Pseudomonas (Cell Host Micr) Time stamps by Jolene. Thanks! Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv