The Peter Attia Drive

Peter Attia, MD
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May 6, 2019 • 2h 54min

#52 - Ethan Weiss, M.D.: A masterclass in cardiovascular disease and growth hormone - two topics that are surprising interrelated

Ethan Weiss, a Hopkins-trained preventative cardiologist at UCSF, dives deep into the fascinating intersection of cardiovascular disease and growth hormone. He unpacks the complexities of heart attacks, the role of stents, and shares groundbreaking insights on the impact of growth hormone on longevity and health. The discussion highlights gender differences in cardiovascular conditions and the nuances of personalized treatment approaches. With anecdotes from his medical journey and a love for hockey, Ethan's expertise and passion light up the conversation.
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16 snips
May 1, 2019 • 1h 3min

The Ayrton Senna Episode (re-release): Celebrating the greatest driver in Formula 1 history and the cautionary tales of driven individuals

In this nostalgic reflection on Ayrton Senna, psychiatrist Paul Conti, a medical school colleague of Peter Attia, reveals the psychological depth behind the iconic F1 driver's prowess. They discuss Senna's legacy, including how his tragic death transformed safety in the sport and the lessons from high-achieving individuals. The duo also shares thrilling tales from the 80s and 90s, highlights memorable rivalries, and dives into the impact of documentaries like 'Senna,' celebrating the blend of talent and ambition that defined an era in motorsport.
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26 snips
Apr 29, 2019 • 2h 19min

#51 - Robert Sapolsky, Ph.D.: The pervasive effect of stress - is it killing you?

In a gripping discussion, Robert Sapolsky, a renowned Stanford professor and author, dives into the complex world of stress and its pervasive effects on health and behavior. He shares insights from his studies on baboons, shedding light on how social hierarchy and personality influence stress responses. Sapolsky explains the physiological mechanisms at play, including the role of cortisol, and reveals how maternal stress can imprint on future generations. He offers practical tips for managing stress in our fast-paced modern world, illuminating how we can improve our well-being.
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Apr 22, 2019 • 12min

#50 - AMA #5: calcium scores, centenarian olympics, exercise, muscle glycogen, keto, and more

Dive into a lively discussion about coronary calcium scores and their significance for heart health. Discover tips on preparing for the unique 'centenarian olympics,' designed to keep you youthful and active. Learn how different exercises affect blood glucose levels and hear about the high-intensity Tabata protocol. Explore the effects of a ketogenic diet on athletic performance and muscle adaptation. Plus, uncover personal insights from Dr. Gabor Maté's work and some quirky trivia like 'pattycakes' and the latest in egg boxing!
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23 snips
Apr 15, 2019 • 2h 1min

#49 – Matthew Walker, Ph.D., on sleep – Part III of III: The penetrating effects of poor sleep from metabolism to performance to genetics, and the impact of caffeine, alcohol, THC, and CBD on sleep

Matthew Walker, a neuroscience and psychology professor at UC Berkeley and director of the Center for Human Sleep Science, dives deep into the critical implications of sleep on health and performance. He explores how poor sleep affects metabolism, decision-making, and productivity. The conversation also examines the negative impacts of caffeine and alcohol on sleep quality, alongside the potential benefits of THC and CBD. Walker highlights the intricate link between sleep and mental health, emphasizing its importance for overall well-being.
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34 snips
Apr 8, 2019 • 2h 5min

#48 – Matthew Walker, Ph.D., on sleep – Part II of III: Heart disease, cancer, sexual function, and the causes of sleep disruption (and tips to correct it)

Matthew Walker, a Professor of Neuroscience at UC Berkeley and sleep expert, dives deep into the crucial role of sleep in our lives. He highlights the alarming links between poor sleep and diseases like cancer and heart disease. Walker discusses how cortisol affects our nervous systems, leading to sleep disruptions, and questions the standard use of sleeping pills. He emphasizes the unique sleep needs of teenagers and advocates for later school start times, while also addressing the detrimental effect of electronics on sleep quality and the benefits of napping.
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38 snips
Apr 1, 2019 • 1h 43min

#47 – Matthew Walker, Ph.D., on sleep – Part I of III: Dangers of poor sleep, Alzheimer's risk, mental health, memory consolidation, and more.

Matthew Walker, a Professor of Neuroscience and Psychology at UC Berkeley, shares his expertise on the crucial role of sleep. He explains the four pillars of sleep and their impact on memory consolidation and mental health. Chronic sleep deprivation significantly increases dementia risk, while drowsy driving poses acute dangers. Walker discusses the unique functions of REM and non-REM sleep, touches on evolutionary aspects, and offers insights on overcoming jet lag. He highlights the growing recognition of sleep's importance in overall health and well-being.
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174 snips
Mar 25, 2019 • 2h 52min

#46 - Chris Masterjohn, Ph.D.: Navigating the many pathways to health and disease - NAD and sirtuins, methylation, MTHFR and COMT, choline deficiency and NAFLD, TMAO, creatine, and more

Chris Masterjohn, Ph.D., an expert in nutrition science and biochemistry, dives into the nuances of health in a fascinating discussion. He sheds light on the role of choline deficiency in non-alcoholic fatty liver disease (NAFLD) and shares insights about how methylation affects overall well-being. The conversation also covers the potential benefits of NAD supplements for aging and health, alongside the significance of the MTHFR and COMT genes. With engaging anecdotes, Chris emphasizes the importance of understanding the complexities of nutrition and health.
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Mar 18, 2019 • 12min

#45 - AMA #4: sleep, jet lag protocol, autophagy, metformin, and more

In this engaging Q&A session, listeners learn about the benefits of blue light blockers for sleep improvement. Strategies to minimize jet lag while traveling are explored, along with insights into hormonal health, including PMS treatment and testosterone levels in women. The concept of autophagy is demystified, highlighting its significance for health. There's also a light-hearted digression on sports, and tips on finding up-to-date doctors in the medical field, all wrapped in a subscriber-centric approach to content.
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Mar 11, 2019 • 1h 42min

#44 - Jeremy Schaap, ESPN journalist: upsets, doping, triumphs, and the importance of sports

Jeremy Schaap, a renowned ESPN journalist and author of "Cinderella Man," dives into boxing's most remarkable upsets, including Buster Douglas's historic win over Mike Tyson. He shares anecdotes from his infamous Bobby Knight interview and discusses the impact of doping scandals in sports. Highlighting the lessons sports impart and the societal issues they reflect, Schaap articulates how following in his father's journalistic footsteps shaped his values. Expect a captivating blend of sports history, ethical dilemmas, and personal reflections.

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